75129-17-8Relevant academic research and scientific papers
Synthesis of Some New Thiazole Derivatives and Their Biological Activity Evaluation
Yurtta?, Leyla,?zkay, Yusuf,Karaca Gen?er, Hülya,Acar, Ulviye
, (2015)
New 2-(4-arylpiperazine-1-yl)-N-[4-(2-(4-substituted phenyl)thiazol-4-yl)phenyl]acetamide derivatives were synthesized and evaluated for their antimicrobial and anticholinesterase activities. Acetylcholinesterase inhibitory activities of the compounds were found weak contrary to expectations. It is unlikely that antifungal activity of the compounds was found significant, especially against Candida parapsilosis.
Synthesis and antiproliferative activity evaluation of new thiazole-benzimidazole derivatives using real-time cell analysis (RTCA DP)
?zkay, Yusuf,Yurtta?, Leyla,Dikmen, Miri?,Engür, Selin
, p. 482 - 493 (2016/02/19)
A series of new 2-[(5-substituted-1H-benzimidazol-2-yl)thio]-N-[4-[2-phenylthiazol-4-yl]phenyl]acetamide derivatives (4a-p) were synthesized according to the reported literature, and anticancer activity of the compounds was evaluated. Cytotoxic activity w
Synthesis and anticancer activities of some thiazole derivatives
Kayagil, Ismail,Demirayak, Seref
scheme or table, p. 2197 - 2207 (2010/04/24)
In this study, 2-substituted 4-[3/4-(4-arylthiazole-2-yl)aminophenyl] thiazole derivatives and 2-[4-[2-substituted 4-methylthiazole-5-yl]thiazole-2- yl]amino-5-arylidenethiazoline-4-one derivatives have been synthesized. The cytotoxic and/or growth inhibitory effects of the 16 selected compounds were evaluated in vitro against approximately 66 human tumor cell lines derived from nine neoplastic diseases. Some of the compounds were found to act as anticancer agents.
