75162-60-6 Usage
Uses
Used in Photodynamic Therapy for Cancer Treatment:
2,4-diacetylhematoporphyrin dimethyl ester is used as a photosensitizing agent for the treatment of various types of cancer, including skin, lung, and bladder cancers. It works by accumulating in tumor tissue and becoming activated upon exposure to a specific wavelength of light, producing toxic substances that kill cancer cells. This targeted approach minimizes damage to healthy cells and offers a promising alternative to traditional cancer therapies.
Used in Photodynamic Therapy for Non-Malignant Conditions:
In addition to its cancer treatment applications, 2,4-diacetylhematoporphyrin dimethyl ester is also used in the treatment of certain non-malignant conditions, such as age-related macular degeneration. By selectively targeting affected cells and activating the DHE with light, the therapy can help slow down or halt the progression of these conditions.
Used in Medical Imaging:
2,4-diacetylhematoporphyrin dimethyl ester can be employed as a contrast agent in medical imaging techniques, such as fluorescence imaging, to enhance the visualization of tumor tissues and other abnormalities. Its selective accumulation in cancer cells allows for more accurate diagnosis and monitoring of treatment efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 75162-60-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,1,6 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 75162-60:
(7*7)+(6*5)+(5*1)+(4*6)+(3*2)+(2*6)+(1*0)=126
126 % 10 = 6
So 75162-60-6 is a valid CAS Registry Number.
75162-60-6Relevant academic research and scientific papers
The Chemistry of Pyrrolic Compounds. XLV. Haematoporphyrin Derivative: Haematoporphyrin Diacetate as the Main Product of the Reaction of Haematoporphyrin with a Mixture of Acetic and Sulfuric Acids
Clezy, Peter S.,Hai, Ton That,Henderson, Robert W.,Thuc, Le van
, p. 585 - 597 (2007/10/02)
A mixture of acetic and sulfuric acids converts haematoporphyrin into a complex mixture of porphyrins of which the main product has been characterized as the diacetate (1g).Other compounds identified in the reaction mixture were the known vinylporphyrins (1b-d), (1h) and (1i) and the isomeric monoacetoxyethyl(monohydroxyethyl)porphyrins (1l) and (1m).Analysis of the reaction mixture was complicated by the presence of 1'-ethoxyethyl derivatives (1e) or (1f), (1j) and (1k) which presumably arose by solvolysis of the corresponding acetate with ethanol present in the chloroform used for the the chromatographic separation.
