75279-60-6

Basic information

• Product Name: (6-Chloro-pyridin-2-yl)-acetonitrile
• Synonyms: (6-Chloro-pyridin-2-yl)-acetonitrile;2-(6-chloropyridin-2-yl)acetonitrile
• CAS NO: 75279-60-6
• Molecular Formula: C₇H₅ClN₂
• Molecular Weight: 152.581
• Mol File: 75279-60-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 270.7 °C at 760 mmHg
• Flash Point: 117.5 °C
• Appearance: /
• Density: 1.262 g/cm³
• Vapor Pressure: 0.00675mmHg at 25°C
• Refractive Index: 1.553
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: -1.57±0.10(Predicted)
• CAS DataBase Reference: (6-Chloro-pyridin-2-yl)-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (6-Chloro-pyridin-2-yl)-acetonitrile(75279-60-6)
• EPA Substance Registry System: (6-Chloro-pyridin-2-yl)-acetonitrile(75279-60-6)

Safety Data

• Hazardous Substances Data: 75279-60-6(Hazardous Substances Data)

Usage

General Description

(6-Chloro-pyridin-2-yl)-acetonitrile is a chemical compound with the molecular formula C7H5ClN2. It is a derivative of pyridine and contains a chloride group at the 6th position and an acetonitrile group at the 2nd position. (6-Chloro-pyridin-2-yl)-acetonitrile is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also used as an intermediate in the preparation of various organic compounds and can be found in research and development laboratories. Additionally, it has potential applications in the field of material science and nanotechnology. Overall, (6-Chloro-pyridin-2-yl)-acetonitrile is a versatile chemical with several industrial and scientific uses.

InChI:InChI=1/C7H5ClN2/c8-7-3-1-2-6(10-7)4-5-9/h1-3H,4H2

Upstream product

• 2402-78-0 2,6-dichloropyridine 
• 75-05-8 acetonitrile 
• 33674-97-4 6-chloro-2-pyridinemethanol 
• 773837-37-9 sodium cyanide 
• 78846-88-5 6-chloro-2-chloromethylpyridine 
• 4684-94-0 6-chloropicolinic acid 

Downstream Products

• 933734-79-3 C₇H₉ClN₂ 
• 1190644-34-8 N-[2-(4-methoxyphenyl)ethyl]-1-(6-chloropyridin-2-yl)cyclobutanecarboxamide 
• 161807-18-7 methyl 2-(6-chloropyridin-2-yl)acetate 
• 905975-90-8 3-amino-5-chloro-2-phenyl-indolizine-1-carbonitrile 
• 905975-92-0 5-chloro-3-(2,4-dimethoxy-benzylamino)-2-phenyl-indolizine-1-carbonitrile 

Relevant articles and documents

PROSTAGLANDIN E2 (PGE2) EP4 RECEPTOR ANTAGONISTS

The present invention relates to novel compounds of formula (I) and pharmaceutical compositions containing these compounds. The compounds provided herein can act as prostaglandin E2 (PGE2) EP4 receptor antagonists, which renders them highly advantageous for use in therapy, particularly in the treatment or prevention of cancer, a neovascular eye disease, inflammatory pain, or an inflammatory disease, such as, e.g., multiple sclerosis, rheumatoid arthritis or endometriosis.

SEPIAPTERIN REDUCTASE INHIBITORS FOR THE TREATMENT OF PAIN

Disclosed herein are small molecule heterocyclic inhibitors of sepiapterin reductase (SPR), and pro-drugs and pharmaceutically acceptable salts thereof. The Also featured are pharmaceutical compositions of the compounds and uses of these compounds for the treatment or prevention of pain (e.g., inflammatory pain, nociceptive pain, functional pain, and neuropathic pain)