75307-67-4

Usage

Uses

Used in Chemical Research and Synthesis:
2,2-dimethyl-1,3-dioxane-4,5,6-trione 5-(phenylhydrazone) is used as a reagent or intermediate in chemical research and synthesis processes for its unique structural properties and potential to facilitate the creation of new compounds.
Used in Pharmaceutical and Medicinal Chemistry:
Although further research is needed, 2,2-dimethyl-1,3-dioxane-4,5,6-trione 5-(phenylhydrazone) may be used as a potential candidate in pharmaceutical and medicinal chemistry due to its distinctive hydrazone functional group, which could offer novel therapeutic or diagnostic applications.

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 2684-02-8 benzenediazonium 
• 64-17-5 ethanol 
• 127-09-3 sodium acetate 
• 66131-14-4 2,2-dimethyl-5,5-dibromo-1,3-dioxane-4,6-dione 
• 100-63-0 phenylhydrazine 
• 62-53-3 aniline 
• 15568-92-0 5-(N-phenyl)-aminomethylene-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 75307-54-9 5-(Benzyloxycarbonyloxy)-2,2-dimethyl-5-(phenyliminomethyl)-1,3-dioxan-4,6-dion 
• 75307-57-2 2,2-dimethyl-5-<<(phenylmethoxy)carbonyl>oxy>-1,3-dioxane-4,6-dione 
• 75307-61-8 2,2-dimethyl-1,3-dioxane-4,5,6-trione 
• 75307-59-4 5-Hydroxy-Meldrums Saeure 

Downstream Products

• 271-44-3 benzimidazole 
• 622-34-4 1-phenylcyanamide 
• 61743-02-0 phenylisocyanoamine 

Relevant academic research and scientific papers

Rapid and clean synthesis of 5-arylhydrazones of Meldrum's acid using polymer supported Meldrum's acid anion

Polymer supported Meldrum's acid anion is treated with various aryl diazonium fluoroborates at 25°C in acetonitrile to give corresponding 5- arylhydrazones of Meldrum's acid in good yield. Isolation of pure products by simple filtration and evaporation is

Reactive Nitrogenous Molecules from Meldrum's Acid Derivatives, Pyrrole-2,3-diones, and Isoxazolones

Flash vacuum pyrolysis of 5-(aminomethylidene)-2,2-dimethyl-1,3-dioxane-4,6-diones (Meldrum's acid derivatives) 12 gives 4-hydroxyquinolines/4-quinolones 15 or 3-enaminoacroleins 22 in good to excellent yields.Intermediate (aminomethylene)ketenes and imidoylketenes are directly observed and their transformation into product 22 monitored by low-temperature IR spectroscopy.Imidoylketenes are also formed and observed upon thermal CO extrusion from pyrrole-2,3-diones 16.Isocyanoamines and fulminates are generated by pyrolysis of hydrazono- or oximino-Meldrum's acid derivatives 32 and 39, monitored by IR spectroscopy, and found to rearrange to cyanamides and cyanates, depending on substituents.The thermal reactions of isoxazol-5(4H)-ones and Meldrum's acid derivatives are compared and discussed.

Introduction of Oxygen Functions into the α-Position of β-Diketones, 4: "Hydroxy- and Oxo-Meldrum's Acids"

Synthesis and properties of 5-hydroxy-, 5-acyloxy-, 5-oxo- and 5,5-dihydroxy-2,2-dialkyl-1,3-dioxane-4,6-diones (6, 5/9, 7, 10) are described.