75370-77-3Relevant academic research and scientific papers
The first Bischler-Napieralski cyclization in a room temperature ionic liquid
Judeh, Zaher M.A.,Ching, Chi Bun,Bu, Jie,McCluskey, Adam
, p. 5089 - 5091 (2002)
We have demonstrated the use of the room temperature ionic liquid, 1-butyl-3-methylimidazoliumhexafluorophosphate ([bmim]PF6), as an environmentally benign solvent for the preparation of isoquinoline derivatives through Bischler-Napieralski cyc
Oxydative Aryl-Aryl-Verknuepfung von 6,6',7,7'-Tetramethoxy-1,1',2,2',3,3',4,4'-octahydro-1,1'-biisochinolin-Derivaten
Siegfried, Marc-Andre,Hilpert, Hans,Rey, Max,Dreidind, Andre S.
, p. 938 - 961 (1980)
We described the synnthesis of 2 by intramolecular oxidative coupling of 1,1'-biisoquinoline derivatives 1 (Scheme 1).This heterocyclic system can be considered as a union of two apomorfine molecules and may thus exhibit dopaminergic activity. - The readi
Synthesis of 1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-11b-methylthiazinoisoquinoline Derivatives
Jirkovsky, I.,Noureldin, R.
, p. 449 - 453 (2007/10/02)
Alkylation of the 2-mercaptoacetamide 4a with chloropropanone afforded the ketoamide 10 which on direct acid-catalyzed cyclization furnished 12.The cyclization can be arrested at the stage of the enamide 11.Periodate oxidation of 12 gave the equatorial su
