7544-64-1 Usage
Uses
Used in Pharmaceutical Applications:
2,4-DIMETHYL-[1,8]NAPHTHYRIDINE is used as a potential anti-inflammatory and anti-cancer agent due to its biological activities. It is being investigated for its ability to modulate various biological pathways and mechanisms associated with inflammation and cancer, offering potential therapeutic benefits in these areas.
Used in Organic Electronic Devices:
2,4-DIMETHYL-[1,8]NAPHTHYRIDINE is used as a component in organic electronic devices, such as organic light-emitting diodes (OLEDs) and organic solar cells, due to its unique electronic and optical properties. Its incorporation into these devices can enhance their performance and efficiency, contributing to the advancement of organic electronics technology.
Used in Medicinal Chemistry Research:
2,4-DIMETHYL-[1,8]NAPHTHYRIDINE is used as a research compound in the field of medicinal chemistry to explore its potential as a lead compound for the development of new drugs. Its diverse biological activities and chemical properties make it a valuable tool for studying and understanding the mechanisms of various diseases and conditions.
Used in Organic Synthesis:
2,4-DIMETHYL-[1,8]NAPHTHYRIDINE is used as a building block or intermediate in the synthesis of other organic compounds, particularly those with potential pharmaceutical or chemical applications. Its unique structure and reactivity make it a versatile component in the development of novel organic molecules.
Used in Materials Science:
2,4-DIMETHYL-[1,8]NAPHTHYRIDINE is used in materials science for the development of new materials with specific properties, such as conductivity, luminescence, or stability. Its unique electronic and optical properties can be harnessed to create materials with improved performance in various applications, including sensors, catalysts, and coatings.
Check Digit Verification of cas no
The CAS Registry Mumber 7544-64-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,5,4 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7544-64:
(6*7)+(5*5)+(4*4)+(3*4)+(2*6)+(1*4)=111
111 % 10 = 1
So 7544-64-1 is a valid CAS Registry Number.
7544-64-1Relevant academic research and scientific papers
Nam, Tae-Gyu,Wijtmans, Maikel,Pratt, Derek A.,Porter, Ned A.
, p. 1397 - 1404 (2005)
n-Alkyllithiums were added to α,α′-disubstituted-1,8- naphthyridines in non-polar solvents such as Et2O-hexane mixtures. In polar solvents such as THF, alkyllithium acts as a base rather than a nucleophile. Regioselective addition was achieved for substrates capable of five-membered cyclic chelation of the (alkyl)lithium reagent. Substrates with a TBS-protected alcohol as the co-chelating moiety afforded the best combination of yield and regioselectivity. This methodology was successfully employed in the preparation of two 6-amino-3-pyridinol analogs of pentamethyl-chromanol (PMC), an a-tocopherol derivative with its isoprenoid side chain truncated to a methyl group. Georg Thieme Verlag Stuttgart.
Method for preparing 1,8-naphthyridine and derivatives
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Paragraph 0035-0037, (2018/02/04)
The invention provides a method for preparing 1,8-naphthyridine and derivatives. The method comprises the following steps of adding an oxidizing agent and a compound in formula (I) or salt thereof into acid, so as to obtain a reaction liquid; stirring and heating the reaction liquid, uniformly dripping a compound in formula (II) to react, cooling to the room temperature, neutralizing by an alkaline solution, and extracting a water phase by solvent, so as to obtain an organic phase; concentrating the organic phase under reduced pressure, and removing the solvent, so as to obtain a compound in formula (III). The method overcomes the defects of low yield and high cost when the 1,8-naphthyridine and derivatives are synthesized by a Skraup method.
