7544-75-4

Basic information

• Product Name: 2-AMINO-1-PYRROLINE HYDROCHLORIDE
• Synonyms: 2-AMINO-1-PYRROLINE HYDROCHLORIDE;4,5-Dihydro-3H-pyrrol-2-ylamine hydrochloride;2H-Pyrrol-5-amine, 3,4-dihydro-, hydrochloride (1:1);2-amino-4,5-dihydro-3H-pyrrole HCl salt;2H-Pyrrol-5-amine, 3,4-dihydro-, monohydrochloride;2-Aminopyrrolidine hydrochloride;3,4-Dihydro-2H-pyrrol-5-aMine hydrochloride;2-AMinopyrrolidine HCl
• CAS NO: 7544-75-4
• Molecular Formula: C₄H₈N₂*ClH
• Molecular Weight: 120.58066
• Product Categories: chemical
• Mol File: 7544-75-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 171.0 to 175.0 °C
• Boiling Point: 211 °C at 760 mmHg
• Flash Point: 81.4 °C
• Appearance: /
• Vapor Pressure: 0.155mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-AMINO-1-PYRROLINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-1-PYRROLINE HYDROCHLORIDE(7544-75-4)
• EPA Substance Registry System: 2-AMINO-1-PYRROLINE HYDROCHLORIDE(7544-75-4)

Safety Data

• RIDADR: UN 1993 3/PG III
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 7544-75-4(Hazardous Substances Data)

Usage

General Description

2-Amino-1-pyrroline hydrochloride is a chemical compound primarily used in the field of scientific research. It is often used for synthesizing other organic compounds. Its molecular formula is C4H8N2·HCl, suggesting that it contains carbon, hydrogen, nitrogen, and chlorine elements. When handled, it comes in the form of a powder, which should be stored in cool, dry conditions away from any potential sources of ignition due to its highly flammable nature. Though not typically hazardous in its handling, proper measures should still be taken to prevent unnecessary exposure or ingestion. It's generally not available for the general public, rather is used in controlled environments such as laboratories or industrial settings.

InChI:InChI=1/C4H8N2.ClH/c5-4-2-1-3-6-4;/h1-3H2,(H2,5,6);1H

Upstream product

• 66996-69-8 2-Methoxypyrroline 
• 5264-35-7 2-methoxy-1-pyrroline 
• 628-20-6 4-Chlorobutyronitrile 
• 616-45-5 2-pyrrolidinon 

Downstream Products

• 101386-17-8 C₁₁H₁₃N₃O₃S 
• 408498-43-1 2-(3-pyridyl)-6,7-dihydro-[5H]-pyrrolo[1,2-a]imidazole 
• 107392-72-3 2-phenyl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole 
• 122454-71-1 2-(pyridin-4-yl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole 
• 117828-45-2 (±)-(3S,3aR,8bR)-8b-hydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-1-one 
• 623564-38-5 6,7-dihydro-5H-pyrrolo[1,2-a]imidazole-2-carbaldehyde 
• 408498-42-0 2-(pyridin-2-yl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole 
• 101386-19-0 C₁₁H₁₂ClN₃O₃S 
• 101386-18-9 C₁₂H₁₅N₃O₃S 

Relevant articles and documents

AN IMPROVED PROCESS FOR THE PREPARATION OF TIPIRACIL HYDROCHLORIDE AND INTERMEDIATES THEREOF

The present invention provides a process for the preparation of Tipiracil HCl of Formula (I) and intermediate thereof with improved yields and purities.

HETEROBICYCLIC ALKYLTHIO-BRIDGED ISOXAZOLINES

Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein J is and R1, R2, R3, R4, R5, R6, R7, R8a, R8b, R8c, G1, G2, G3, G4, G5, G6, Q1, Q2, Q3, Q4, W1, W2, Y1, Y2, Y3, m and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.

Cyclic amidine analogs as inhibitors of nitric oxide synthase

Disclosed herein are compounds of Formula I STR1 and pharmaceutically acceptable salts thereof which have been found useful in the treatment of nitric oxide synthase mediated diseases and disorders, including neurodegenerative disorders, disorders of gastrointestinal motility and inflammation. These disease and disorders include hypotension, septic shock, toxic shock syndrom, hemodialysis, IL-2 therapy such as in cancer patients, cachexia, immunosuppression such as in transplant therapy, autoimmune and/or inflammatory indications including sunburn or psoriasis and respiratory conditions such as bronchitis, asthma, and acure respiratory distress (ARDS), myocarditis, heart failure, atherosclerosis, arthritis, rheumatoid arthritis, chronic or inflammatory bowel disease, ulcerative colitis, Crohn's disease, systemic lupus erythematosis (SLE), ocular conditions such as ocular hypertension and uveitis, type 1 diabetes, insulin-dependent diabetes mellitus and cystic fibrosis. Compounds of Formula I are also usful in the treatment of hypoxia, hyperbaric oxygen convulsions and toxicity, dementia, Sydenham's chorea, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, mulitple sclerosis, Korsakoff's disease, imbecility related to cerebral vessel disorder, ischemic brain edema, sleeping disorders, schizophrenia, depression, PMS, anxiety, drug addiction, pain, migraine, immune complex disease, as immunosupressive agents and for preventing or reversing tolerance to opiates and diazepines.