75472-91-2 Usage
Uses
Desacetyl Diltiazem Hydrochloride is a metabolite of Diltiazem Hydrochloride (D460620), a calcium channel blocher with vasodilating activity. Antianginal; antihypertensive; antiarrhythmic (class IV).
Check Digit Verification of cas no
The CAS Registry Mumber 75472-91-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,4,7 and 2 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 75472-91:
(7*7)+(6*5)+(5*4)+(4*7)+(3*2)+(2*9)+(1*1)=152
152 % 10 = 2
So 75472-91-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H24N2O3S.ClH/c1-21(2)12-13-22-16-6-4-5-7-17(16)26-19(18(23)20(22)24)14-8-10-15(25-3)11-9-14;/h4-11,18-19,23H,12-13H2,1-3H3;1H/t18-,19+;/m1./s1
75472-91-2Relevant articles and documents
Process for preparing diltiazem using a heterogeneous trifunctional catalyst
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Page 3, (2008/06/13)
The present invention comprises a simplified synthesis of (+)-diltiazem through IE-PdOsW wherein IE is ion-exchanger, catalyzed three-component coupling reaction and Fe3+-exchanged clay catalyzed ring opening of sulfite with 2-aminothiophenol followed by cyclization as key steps.