75476-84-5 Usage
Uses
Used in Pharmaceutical Synthesis:
Isoquinoline, 6-iodo(9CI) is utilized as a key building block in the synthesis of various pharmaceuticals and organic compounds. Its unique structure and reactivity make it a promising candidate for the development of new drugs and therapeutic agents.
Used in Research and Development Laboratories:
Isoquinoline, 6-iodo(9CI) is employed in research and development laboratories for its potential applications in drug discovery and medicinal chemistry. Its versatile reactivity and biological activities, such as anti-inflammatory and anti-cancer properties, contribute to the advancement of scientific knowledge and the development of innovative treatments.
Used in Drug Discovery:
Isoquinoline, 6-iodo(9CI) is used as a starting material in drug discovery, where its unique chemical properties and potential biological activities are explored for the development of new therapeutic agents. Its presence in various synthetic pathways allows researchers to create novel compounds with potential medicinal applications.
Used in Medicinal Chemistry:
Isoquinoline, 6-iodo(9CI) is applied in medicinal chemistry for its potential to contribute to the design and synthesis of new drugs. Its structural features and reactivity make it a valuable component in the creation of compounds with specific therapeutic targets, enhancing the effectiveness of treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 75476-84-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,4,7 and 6 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 75476-84:
(7*7)+(6*5)+(5*4)+(4*7)+(3*6)+(2*8)+(1*4)=165
165 % 10 = 5
So 75476-84-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H6IN/c10-9-2-1-8-6-11-4-3-7(8)5-9/h1-6H
75476-84-5Relevant academic research and scientific papers
NOVEL COMPOUNDS AS PHARMACEUTICAL AGENTS
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Page 92-93, (2010/02/07)
The current invention relates to compounds of the formula:(Ia) and the pharmaceutically acceptable salts thereof and their use as TGF-beta signal transduction inhibitors for treating cancer and other diseases in a patient in need thereof by administration of said compounds.
Synthesis of Isoquinolines from Indenes
Miller, R. Bryan,Frincke, James M.
, p. 5312 - 5315 (2007/10/02)
A general procedure for the synthesis of isoquinolines from appropriately substituted indenes is described.Ozonolysis of the indenes followed by reductive workup gives intermediate homophthalaldehydes which are treated with ammonium hydroxide to give the isoquinolines.This "one-pot", three-step reaction sequence was applied to the formation of all of the mono-C-methyl-substituted isoquinolines in a regiospecific manner.The procedure is applicable to both electron-withdrawing and electron-donating substituents on the indene system.In this manner the 6- and 7-nitro-,-bromo-, and -iodoisoquinolines were prepared.
