75487-82-0

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 6-fluoro-
• Synonyms: 6-fluorocoumarin;6-fluoro-coumarin;6-fluoro-chromen-2-one;8-fluorocoumarin;6-Fluorcoumarin
• CAS NO: 75487-82-0
• Molecular Formula: C9H5FO2
• Molecular Weight: 164.13300
• Mol File: 75487-82-0.mol
• Article Data: 9

Chemical Properties

• Melting Point: 167 - 168 °C
• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 6-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 6-fluoro-(75487-82-0)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 6-fluoro-(75487-82-0)

Safety Data

• Hazardous Substances Data: 75487-82-0(Hazardous Substances Data)

Upstream product

• 371-41-5 4-Fluorophenol 
• 617-48-1 malic acid 
• 141-82-2 malonic acid 
• 347-54-6 5-fluoro-2-hydroxybenzaldehyde 
• 4279-77-0 S-phenyl hydrogen thiomalonate 
• 108-31-6 maleic anhydride 
• 949449-09-6 3-(5-fluoro-2-hydroxyphenyl)acrylic acid ethyl ester 
• 108-24-7 acetic anhydride 
• 452-08-4 2-bromo-4-fluoro-1-methoxybenzene 
• 64-18-6 formic acid 
• 91-64-5 coumarin 
• 223778-71-0 ethyl 3-(5'-fluoro-2'-methoxyphenyl)-2-propenoate 

Relevant articles and documents

Synthesis, characterization, optical properties and theoretical calculations of 6-fluoro coumarin

6-Fluoro coumarin is synthesized and characterized by 1H NMR and 13C NMR. The optical properties of the title compound are investigated by UV-vis absorption and fluorescence emission spectra, the results show the title compound can a

Visible-light-induced regioselective alkylation of coumarins via decarboxylative coupling with N-hydroxyphthalimide esters

An efficient photocatalytic decarboxylative 3-position alkylation of coumarins by using alkyl N-hydroxyphthalimide esters as alkylation reagents has been developed. A variety of NHP esters derived from aliphatic carboxylic acids (primary, secondary, and tertiary) has been proved to be tolerated for this decarboxylation process, affording a broad scope of 3-alkylated coumarin derivatives in moderate to excellent yields. This protocol was highlighted by its mild conditions, readily available starting materials, operational simplicity, and wide functional group tolerance.

Amine-catalyzed cascade synthesis of 3,4-diunsubstituted coumarins

We disclose an efficient route to synthesize 3,4-diunsubstituted coumarins through a cascade organocatalytic reaction. The reaction is catalyzed by using of a combination of benzylamine (10 mol-%) and triethylamine (10 mol-%). Various salicylaldehydes were tested, and the corresponding coumarin products were obtained in good to high yields under mild and metal-free reaction conditions. We disclose an efficient route to synthesize 3,4-diunsubstituted coumarins through a cascade organocatalytic reaction. The reaction is catalyzed by using of a combination of benzylamine (10 mol-%) and triethylamine (10 mol-%). Various salicylaldehydes are tested, and the corresponding coumarin products are obtained in good to high yields under mild and metal-free reaction conditions. Copyright