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75501-05-2

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75501-05-2 Usage

Uses

The major urinary metabolite of Mebendazole (M200500) in man.

Check Digit Verification of cas no

The CAS Registry Mumber 75501-05-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,5,0 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 75501-05:
(7*7)+(6*5)+(5*5)+(4*0)+(3*1)+(2*0)+(1*5)=112
112 % 10 = 2
So 75501-05-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H13N3O/c15-14-16-11-7-6-10(8-12(11)17-14)13(18)9-4-2-1-3-5-9/h1-8,13,18H,(H3,15,16,17)

75501-05-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Amino-5(6)-[α-hydroxybenzyl]benzimidazole

1.2 Other means of identification

Product number -
Other names (2-amino-3H-benzimidazol-5-yl)-phenylmethanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:75501-05-2 SDS

75501-05-2Relevant articles and documents

Studies in Antiparasitic Agents: Part 8 - Synthesis of 2-Substitutedamino-5(6)-benzoylbenzimidazoles as Structural Analogs of Mebendazole Metabolites

Singh, Sudhir K.,Naim, S. Shawkat,Sharma, Satyavan

, p. 1015 - 1018 (2007/10/02)

The synthesis of a series of 2-substitutedamino-5(6)-benzoylbenzimidazoles (6-22) has been carried out as the structural analogs of 2-amino-5(6)-benzoyl/α-hydroxy-α-phenylmethylbenzimidazoles (3, 4), the two metabolites of mebendazole.The compounds 6-22 have been tested for their anthelmintic activity against Ancylostoma ceylanicum, Nippostrongylus brasiliensis and Hymenolepis nana in rodents.Compounds 9, 11, 12, 13 and 14 exhibit 100percent elimination of A. ceylanicum worms from the animals at a single oral dose of 50-250 mg/kg.Some of the compounds also show activity against H. nana and N. brasiliensis.

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