7559-62-8Relevant articles and documents
Chemically modified enzymes
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, (2008/06/13)
Modified enzymes are provided in which at least one amino acid, such as asparagine, leucine, methionine or serine, of an enzyme is replaced with a cysteine and the thiol hydrogen is replaced with a substituent group providing a thiol side chain selected from the group consisting of: a) —SR1R2, wherein R1is an alkyl and R2is a charged or polar moiety; b) —SR3, wherein R3is a substituted or unsubstituted phenyl; c) —SR4, wherein R4is substituted or unsubstituted cyclohexyl; d) —SR5, wherein R5is C10-C15alkyl; and e) —SR6wherein R6is a C1-6alkyl. Also, methods of producing the modified enzymes are provided, as well as detergent and feed additives and a composition for the treatment of a textile. A method for using the modified enzymes in organic synthesis is additionally provided. Further, modified enzymes having improved activity, altered pH profile and/or wash performance are provided.
REACTION OF THIOLSULFINATES WITH TRIHALOACETIC ANHYDRIDES-I EVIDENCE FOR THE FORMATION OF SULFENYL AND SULFINYL CARBOXYLATES
Morishita, Tsuyoshy,Furukawa, Naomichi,Oae, Shigeru
, p. 3115 - 3120 (2007/10/02)
Thiosulfinates react with trifluoro- or trichloroacetic anhydride to give equimolar mixtures of the coresponding disulfides and sulfinyl trifluoro- or trichloroacetates which are in equilibria with sulfenyl carboxylates.Although the equilibrium lies far toward sulfinyl carboxylates at room temperature, addition of olefins to the mixed solution of sulfinyl carboxylate and corresponding disulfide affords the adducts which are formed in the reaction between the corresponding sulfenyl carboxylates and the olefins.Meanwhile, treatment of carboxylic acid silver salts with sulfinyl chlorides also gives sulfinyl carboxylates, howevver, sulfinyl carboxylates have not been successfully isolated yet.