756-09-2

Usage

Uses

Used in Chemical Synthesis Industry:
3H-Tetrafluoropropionic acid is used as a precursor for the production of 2,2,3,3-tetrafluoro-propionyl chloride. This synthesis is facilitated by the use of benzotrichloride as a reagent, which aids in the conversion of the acid into the desired chloride compound. The resulting tetrafluoro-propionyl chloride can be further utilized in various chemical reactions and applications, such as the synthesis of pharmaceuticals, agrochemicals, and specialty materials that require fluorinated building blocks.

InChI:InChI=1/C3H2F4O2/c4-1(5)3(6,7)2(8)9/h1H,(H,8,9)/p-1

Upstream product

• 116-14-3 polytetrafluoroethylene 
• 143-33-9 sodium cyanide 
• 129657-55-2 ethyl (4,4,5,5-tetrafluoro-3-oxy-3-tert-butylperoxy)pentanoate 
• 66-71-7 1,10-Phenanthroline 
• 76-37-9 2,2,3,3-tetrafluoropropanol 
• 52-68-6 trichlorfon 
• 337-83-7 2,2,3,3-tetrafluoropropionic acid anhydride 
• 215858-32-5 2,2,3,3-tetrafluoropropionaldehyde hydrate 

Downstream Products

• 661-82-5 3-Chlor-2,2,3,3-tetrafluor-propionsaeure 
• 337-83-7 2,2,3,3-tetrafluoropropionic acid anhydride 
• 1579-57-3 2,2,3,3-tetrafluoro-propionic acid-(4-chloro-anilide) 
• 663-73-0 α,α,β,β-tetrafluoropropionic acid chloride 
• 2252-84-8 HFC-227ca 
• 1893-38-5 methyl 2,2,3,3-tetrafluoropropionate 

Relevant academic research and scientific papers

PYRIMIDONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS

The present disclosure is directed to pyrimidone derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV nave cells, and for the treatment or prophylaxis of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).

PYRIDINONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS

The present disclosure is directed to pyridinone derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV nave cells, and for the treatment of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).

Polyfluoroalkoxy phosphonic and phosphinic acid derivatives: II. Reversible esterase inhibitors

Polyfluoroalkyl esters of phosphoric, alkylphosphonic and 1-hydroxypolyfluoroalkylphosphonic acids exhibited significant antiesterase activity against various esterases of animal and microbial origin. Moreover, with some compounds reversible inhibition of enzymes was observed due to the specific influence of hydrophobic fragments of the target products.

Ozonolysis of alkenes and studies of reactions of polyfunctional compounds: LXIII.* Ozonolysis of 2,3,3,4,4,-pentafluoro-1-methoxycyclobutene

Ozonolysis of 2,3,4,4-pentafluoro-1-methoxycyclobutene in Freon-113 leads to formation of cyclic products containing eight fluorine atoms. Ozonolysis of the same compound in Freon-113 in the presence of alcohols yields the corresponding alkyl methyl perfluorosuccinate.

Method for preparing α-substituted ω-hydroperfluoroalkanes

A method for the preparation of α-substituted ω-dihydroperluoroalkane derivatives of the general formula H(CF2 CF2)n R wherein R=H or COOH, and n=1-10 is characterized by oxidizing α, α, ω-trihydroperfluoroalcohols with an oxygen gas or an oxygen-containing gas in the presence of a homogeneous copper catalyst and an alkaline agent in an organic solvent with subsequent isolation of the desired product.

THERMAL DECOMPOSITION OF PEROXIDE DERIVATIVES OF POLYFLUORINATED β-KETOESTERS

The thermal flow microcalorimetric method was used to determine the kinetic parameters for the thermal decomposition of peroxide derivatives of polyfluorinated β-ketoesters and the decomposition products were established.