756470-95-8Relevant academic research and scientific papers
Labelled compound capable of improving Tm value of oligonucleotide chain and application thereof
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Paragraph 0023; 0024; 0025; 0026, (2018/03/26)
The invention relates to a labelled compound (I) capable of improving the Tm value of an oligonucleotide chain and an application thereof. The invention has the following main beneficial effects: thelabelled compound (HT succinate) capable of improving the Tm value of the oligonucleotide chain and the application thereof provided by the invention can effectively identify wild type and mutant typetemplates of DPYD * 9A loci by adopting a HT labelled probe, can be used for detecting tumors of a digestive system, and has important application prospects.
Antitumor AHMA linked to DNA minor groove binding agents: Synthesis and biological evaluation
Rastogi, Kamesh,Chang, Jang-Yang,Pan, Wen-Yu,Chen, Ching-Huang,Chou, Ting-Chao,Chen, Li-Tzong,Su, Tsann-Long
, p. 4485 - 4493 (2007/10/03)
DNA minor groove binder hybrid molecules, netropsin derivatives such as N-[2-(dimethylamino)-ethyl]-1-methyl-4-aminopyrrolo-2-carboxamide (MePy) or its derivatives containing two units of N-methylpyrrolecarboxamide (diMePy) and bisbenzimidazole (Ho33258),
