75679-58-2

Basic information

• Product Name: 2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone
• Synonyms: 2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone
• CAS NO: 75679-58-2
• Molecular Formula: C₁₇H₁₈O₅
• Molecular Weight: 302.32182
• Mol File: 75679-58-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 169-170 °C(Solv: dichloromethane (75-09-2); methanol (67-56-1))
• Boiling Point: 503.5°Cat760mmHg
• Flash Point: 184.7°C
• Appearance: /
• Density: 1.243g/cm³
• Vapor Pressure: 9.24E-11mmHg at 25°C
• Refractive Index: 1.594
• PKA: 7.31±0.40(Predicted)
• CAS DataBase Reference: 2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone(CAS DataBase Reference)
• NIST Chemistry Reference: 2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone(75679-58-2)
• EPA Substance Registry System: 2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone(75679-58-2)

Safety Data

• Hazardous Substances Data: 75679-58-2(Hazardous Substances Data)

Usage

General Description

2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone is a chemical compound that is found in various plants and has been studied for its potential health benefits. It belongs to the class of dihydrochalcones and is known for its antioxidant properties. Studies have shown that this compound may have anti-inflammatory, anti-cancer, and anti-diabetic effects. It has also shown potential in improving cardiovascular health and reducing the risk of various chronic diseases. Overall, 2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone is a promising compound with various potential health benefits, and further research is needed to fully understand its mechanisms and potential applications.

InChI:InChI=1/C17H18O5/c1-21-13-6-3-11(4-7-13)5-8-14(19)17-15(20)9-12(18)10-16(17)22-2/h3-4,6-7,9-10,18,20H,5,8H2,1-2H3

Upstream product

• 56121-44-9 (2E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one 
• 855740-21-5 2′,4′-dihydroxy-4,6′-dimethoxychalcone 
• 3602-54-8 4,6-dihydroxy-2-methoxyacetophenone 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 84457-62-5 2'-hydroxy-4'-benzyloxy-4,6'-dimethoxychalkone 
• 123-11-5 4-methoxy-benzaldehyde 
• 39548-89-5 1-(4-(benzyloxy)-2-hydroxy-6-methoxyphenyl)ethan-1-one 
• 2174-64-3 5-methoxyresorcinol 
• 22442-48-4 3-(4-methoxyphenyl)propionitrile 

Downstream Products

• 75679-64-0 2'-acetoxy-4,4',6'-trimethoxydihydrochalkone 
• 3791-75-1 2'-hydroxy-4,4',6'-trimethoxydihydrochalcone 
• 75679-63-9 2',4'-diacetoxy-4,6'-dimethoxydihydrochalkone 

Relevant articles and documents

Natural chalcones elicit formation of specialized pro-resolving mediators and related 15-lipoxygenase products in human macrophages

Specialized pro-resolving mediators (SPMs) comprise lipid mediators (LMs) produced from polyunsaturated fatty acids (PUFAs) via stereoselective oxygenation particularly involving 12/15-lipoxygenases (LOXs). In contrast to pro-inflammatory LMs such as leuk

COMPOUNDS, THEIR SYNTHESES, AND THEIR USES

Embodiments of the present invention provide compounds (such as Formula (I) compounds, Formula (II) compounds, and various embodiments thereof). Compositions comprising those compounds are also provided. Methods for their preparation are included. Also, uses of the compounds are included, such as administering and treating diseases (e.g., cancer and infections).

Syntheses of Two New Naturally Occurring Dihydrochalkones, Uvangolatin and 2',4'-Dihydroxy-4,6'-dimethoxydihydrochalkone

The structures proposed for the two naturally occurring dihydrochalkones, uvangolatin isolated from Uvaria angolensis as 2',4'-dihydroxy-6'-methoxydihydrochalkone (I) and another dihydrochalkone isolated from Iryanthera laevis as 2',4'-dihydroxy-4,6'-dime