75716-86-8

Basic information

• Product Name: α-(4-methylphenyl)-α-oxoacetic acid tert-butyl ester
• Synonyms: α-(4-methylphenyl)-α-oxoacetic acid tert-butyl ester
• CAS NO: 75716-86-8
• Molecular Weight: 220.268
• Mol File: 75716-86-8.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: α-(4-methylphenyl)-α-oxoacetic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: α-(4-methylphenyl)-α-oxoacetic acid tert-butyl ester(75716-86-8)
• EPA Substance Registry System: α-(4-methylphenyl)-α-oxoacetic acid tert-butyl ester(75716-86-8)

Safety Data

• Hazardous Substances Data: 75716-86-8(Hazardous Substances Data)

Upstream product

• 106-38-7 para-bromotoluene 
• 75716-83-5 tert-butyl α-oxo-1H-imidazole-1-acetate 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 39061-59-1 t-butoxalyl chloride 
• 183241-90-9 C₁₀H₁₅N₃O₃ 
• 50624-94-7 oxalic acid tert-butyl ester ethyl ester 
• 105457-91-8 2-oxo-2-(p-tolyl)acetyl chloride 
• 75-65-0 tert-butyl alcohol 
• 122-00-9 para-methylacetophenone 
• 7163-50-0 (4-methylphenyl)(oxo)acetic acid 
• 66616-85-1 α-(4-methylphenyl)acrylic acid 
• 2769-72-4 tert-Butyl isocyanoacetate 
• 585526-04-1 N-(4-methoxy-4-methylcyclohexa-2,5-dien-1-ylidene)-4-methylbenzenesulfonamide 
• 599-86-0 4-methyl-N-(4-methylphenyl)benzenesulfonamide 

Downstream Products

• 131323-07-4 1,1-dimethylethyl 2-(4-methylphenyl)-2,2-difluoroacetate 
• 1310929-13-5 C₁₈H₂₅NO₄ 
• 1279018-03-9 (S)-tert-butyl 2-((S)-3,4-dichloro-2,5-dihydro-5-oxofuran-2-yl)-2-hydroxy-2-p-tolylacetate 
• 1279018-30-2 (S)-tert-butyl 2-((S)-3,4-dibromo-5-oxo-2,5-dihydrofuran-2-yl)-2-hydroxy-2-p-tolylacetate 
• 222843-57-4 benzyl (2R,3S)-3-<4-(tert-butoxycarbonyl-difluoro-methyl)phenyl>-2-oxo-5,6-diphenyl-morpholine-4-carboxylate 
• 222843-03-0 N-Fmoc-4-(tert-butoxycarbonyl-difluoro-methyl)-L-phenylalanine 
• 222842-94-6 4-(tert-butoxycarbonyl-difluoro-methyl)-L-phenylalanine 
• 127152-63-0 1,1-dimethylethyl 2-(4-bromomethylphenyl)-2,2-difluoroacetate 
• 543720-19-0 (3S,5S,6R)-3-(4-tert-Butoxyoxalyl-benzyl)-2-oxo-5,6-diphenyl-morpholine-4-carboxylic acid benzyl ester 
• 543720-21-4 3-[4-(tert-butoxycarbonyl-hydroxy-methyl)-phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid 
• 543720-20-3 2-amino-3-[4-(tert-butoxycarbonyl-hydroxy-methyl)-phenyl]-propionic acid 
• 543720-18-9 (4-bromomethyl-phenyl)-oxo-acetic acid tert-butyl ester 
• 7163-50-0 (4-methylphenyl)(oxo)acetic acid 

Relevant articles and documents

Preparation of asymmetric phase-transfer catalyst, 1,4-bis((4s,5s)-1,3-bis(3,5-di-tert-butylbenzyl)-4,5-diphenylimidazolidin-2-ylidene)piperazine-1,4-diium chloride

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Destruction and Construction: Application of Dearomatization Strategy in Aromatic Carbon-Nitrogen Bond Functionalization

The formation of carbon-carbon bonds through the functionalization of aromatic carbon-nitrogen bonds is a highly attractive synthetic strategy in the synthesis of aromatic molecules. In this paper, we report a novel aromatic carbon-nitrogen bond functionalization reaction by using a simple dearomatization strategy. Through this process para-substituted anilines serve as a potential aryl source in the construction of a range of functionalized aromatic molecules, such as quaternary carbon centers, α-keto esters, and aldehydes.

Organocatalytic Enantioselective Michael Reaction of Malononitrile with β,β-Disubstituted Nitroalkenes

We have developed and optimized an enantioselective Michael reaction of malononitrile with β,β-disubstituted nitroalkenes. This reaction was catalyzed by a cinchona alkaloid derived thiourea catalyst, producing products of high yields (up to 98 %) and ste