75748-96-8Relevant academic research and scientific papers
A facile preparation of phthalimides and a new approach to the synthesis of indoprofen via carbonylation
Prasad, Chalasani S.N.,Varala, Ravi,Adapa, Srinivas R.
, p. 281 - 286 (2002)
This report describes an improved synthesis of a heterocyclic propionic acid, 2-4(1-oxo-2-isoindolinyl) phenyl propionic acid, Indoprofen (I) via carbonylation, a potent anti-inflammatory agent1 and an analgesic. The synthesis highlights the preparation of Indoprofen starting from readily available o-toluic acid and p-amino acetophenone by a sequence of reactions that included oxidative addition of carbonylation.
METHODS AND COMPOSITIONS TO TREAT MOTOR NEURON DISEASE
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Page/Page column 20, (2008/06/13)
The invention features compositions and methods for treating motor neuron diseases, such as spinal muscular atrophy and amyotrophic lateral sclerosis. The compositions and methods include derivatives of indoprofen.
