75762-23-1

Usage

Uses

Used in Perfume and Cosmetics Industry:
METHYL BENZOOXAZOL-2-YL-ACETATE is used as a flavoring and fragrance ingredient for its ability to add a pleasant aroma to perfumes, cosmetics, soaps, and other personal care products. Its sweet, floral, and fruity scent enhances the sensory experience of these products, making them more appealing to consumers.
Used in Food Industry:
METHYL BENZOOXAZOL-2-YL-ACETATE is used as a flavor additive for its capacity to impart a desirable taste and aroma to various food products. It is particularly utilized in the production of baked goods, confectionery, and beverages, where it contributes to the overall flavor profile and consumer enjoyment of these items.

Upstream product

• 95-21-6 2-methyl-1,3-benzoxazole 
• 79-22-1 methyl chloroformate 
• 15344-56-6 2-(benzo[d]oxazol-2-yl)acetonitrile 
• 67-56-1 methanol 
• 95-55-6 2-amino-phenol 
• 108-59-8 malonic acid dimethyl ester 
• 17691-75-7 3-(diethylamino)propynoic acid methyl ester 

Downstream Products

• 78756-98-6 2-(benzoxazol-2-yl)acetic acid 
• 6797-13-3 2-ethyl-1,3-benzoxazole 
• 936551-14-3 C₂₅H₂₁O₃N 
• 936551-24-5 C₂₀H₁₉O₃N 
• 936551-23-4 C₂₈H₂₇O₃N 
• 936551-13-2 C₁₉H₁₇O₃N 

Relevant academic research and scientific papers

Bidentate oxazoline-imine ruthenium(II) complexes: Intermediates in the methanolysis/hydration of nitrile groups

The reaction of [RuCl2(p-cymene)]2 with benzoxazoleacetonitriles and NH4+BF4 - in methanol leads to bidentate N,N′-benzoxazole-methoxyimine- ruthenium(II) complexes 7, corresponding to the addition of methanol to the ruthenium(II)-activated nitrile triple bond. The X-ray structure of a complex 7 shows equivalent Ru-N and slightly different C=N bond distances. The catalytic hydration of benzoxazolacetonitriles with [RuCl2(p-cymene)] 2 in methanol/water leads to quantitative formation of corresponding amides under mild conditions.

Regio- and diastereoselective decarboxylative coupling of heteroaromatic alkanes

Allylic esters of heteroaromatic alkanes undergo facile palladium-catalyzed decarboxylative coupling. The resulting C-C bond is formed with high diastereoselectivity and high regioselectivity for coupling at the more substituted allyl terminus. It is proposed that this unusual combination of selectivities results from a tandem allylation/aza-Cope rearrangement sequence. After allylation, decarboxylative dearomatization produces an intermediate for the aza-Cope rearrangement. The subsequent aza-Cope rearrangement occurs under mild conditions because it is driven by rearomatization. Copyright

Catalytic asymmetric cyclopropanation of heteroaryldiazoacetates

Rh2(S-DOSP)4-catalyzed decomposition of heteroaryldiazoacetates in the presence of styrene results in highly diastereoselective and enantioselective cyclopropanations. Heteroaryldiazoacetates containing both electron-rich and electron-deficient heterocycles, such as thiophene, furan, pyridine, indole, oxazole, isoxazole, and benzoxazole, are effective in this chemistry. These studies broaden the range of diazo compounds containing both electron-withdrawing and electron-donating groups, which undergo highly diastereoselective cyclopropanations.

METHYL DIALKYLAMINOPROPIOLATES IN REACTIONS WITH BIFUNCTIONAL COMPOUNDS

Methyl dialkylaminopropiolates react with bifunctional reagents with the formation of heterocyclic compounds, and the direction of the reaction is determined by the type of bifunctional group. 1,2-Diamines (ethylenediamine, o-phenylenediamine) add at both reaction centers of the substrate, forming seven-membered heterocycles of the diazepinone and benzodiazepinone series. o-Aminophenol and o-aminothiophenol react exclusively at the ynamine fragment, and 2-substituted benzoxazole and benzothiazole are produced as a result of cyclization.