75772-03-1

Upstream product

• 58-86-6 D-xylose 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 20881-04-3 1,2:3,5-di-O-isopropylidene-D-xylofuranose 
• 75783-45-8 (3aR,5R,6aS)-5-[[(tert-butyldiphenylsilyl)oxy]methyl]-2,2-dimethyltetrahydro-2H-furo[2,3-d][1,3]dioxol-6-one 
• 114861-14-2 1,2-O-isopropylidene-5-O-(t-butyldiphenylsilyl)-α-D-xylofuranose 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 

Downstream Products

• 69827-90-3 5-O-benzoyl-3-C-benzoyloxymethyl-3-deoxy-1,2-O-isopropylidene-α-D-ribo-pentofuranose 
• 130469-49-7 5-O-benzoyl-3-deoxy-3-<(benzoyloxy)methyl>-1,2-di-O-acetyl-β-D-ribofuranose 
• 130469-50-0 6-chloro-9-<5-O-benzoyl-3-deoxy-3-<(benzoyloxy)methyl>-2-O-acetyl-β-D-ribofuranosyl>-9H-purine 

Relevant academic research and scientific papers

1,2-Isopropylidene Furanoses as Chiral Precursors for α-Methylene-γ-butyrolactones

1,2-O-isopropylidene furanose derivatives may be converted into syn or anti forms of the title lactones, via 2-C-methylene glycofuranosides which are hydrolysed under neutral conditions.

3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV

Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either al

Synthesis of novel D- and L-3′-deoxy-3′-C-Hydroxymethyl nucleoside with exocyclic methylene as potential ribonucleotide reductase inhibitor

D- and L-3′-Deoxy-3′-C-hydroxymethyl thymidine substituted with exocyclic methylene at 2′-position were synthesized, starting from D- and L-xylose as potential ribonucleotide reductase inhibitor, respectively, but they were found to be inactive against several tumor cell lines.