7578-51-0Relevant academic research and scientific papers
A facile route to flavone and neoflavone backbones via a regioselective palladium catalyzed oxidative Heck reaction
Khoobi, Mehdi,Alipour, Masoumeh,Zarei, Samaneh,Jafarpour, Farnaz,Shafiee, Abbas
, p. 2985 - 2987 (2012/04/04)
A straightforward and atom-economical base-free palladium-catalyzed regioselective direct arylation of coumarins and chromenones is devised. This protocol is compatible with a wide variety of electron-donating and -withdrawing substituents and allows construction of various biologically important flavone and neoflavone backbones.
Solution phase synthesis of a combinatorial library of chalcones and flavones as potent cathepsin v inhibitors
Alvim, Joel,Severino, Richele P.,Marques, Emerson F.,Martinelli, Ariane M.,Vieira, Paulo C.,Fernandes, Joao B.,Da Silva, M. Fatima Das G. F.,Correa, Arlene G.
experimental part, p. 687 - 695 (2010/11/18)
Cathepsin V is a papain-like cysteine protease. It is involved in the control of human T cells (responsible for cell immunity), and presents the largest elastolytic activity among the proteolytic enzymes. Therefore, cathepsin V is a potential molecular ta
First total synthesis of two 5-deoxyflavone derivatives from Albizia odoratissima
Gao, Jin-Ming,Lu, Jia-Wen,Zhang, An-Ling,Cheng, Yong-Xian,Watchueng, Jean,Konishi, Yasuo
, p. 163 - 164 (2007/10/03)
The first total synthesis of two unusual 5-deoxyflavone derivatives from Albizia odoratissima, 7,8-dimethoxy-3′,4′-methylenedioxyflavone 1 and 7,2′,4′-trimethoxy-flavone 2, has been accomplished.
ONE-STEP CONVERSION OF FLAVANONES INTO ISOFLAVANONES: A NEW FACILE BIOMIMETIC SYNTHESIS OF ISOFLAVONES
Kinoshita, Takeshi,Ichinose, Koji,Sankawa, Ushio
, p. 7355 - 7356 (2007/10/02)
One-step chemical conversion of flavanones into isoflavones by use of thallium trinitrate (TTN) is reported, and the mechanism of a 2,3-aryl migration in this reaction is discussed in relation to in vivo rearrangement process of flavanone precursors in the isoflavone biosynthesis.
