757951-86-3

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 174868-40-7 methyl 4-(benzyloxy)-3,7,8,9-tetrahydro-8-hydroxy-6-(methoxycarbonyl)-6H-pyrrolo[3,2-f]quinoline-2-carboxylate 
• 757951-83-0 methyl 7-benzyloxy-1-methanesulfonyl-5-(N-methoxycarbonylamino)-4-(1-propyn-3-ol)indole-2-carboxylate 
• 757951-84-1 7-benzyloxy-4-(3-hydroxy-propenyl)-1-methanesulfonyl-5-methoxycarbonylamino-1H-indole-2-carboxylic acid methyl ester 
• 757951-82-9 methyl 7-benzyloxy-4-iodo-1-methanesulfonyl-5-(N-methoxycarbonylamino)indole-2-carboxylate 
• 121-88-0 5-Nitro-2-aminophenol 
• 757951-81-8 5-amino-7-benzyloxy-4-iodo-1-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester 
• 757951-76-1 methyl 7-benzyloxy-1-methanesulfonyl-5-nitroindole-2-carboxylate 
• 757951-79-4 C₁₅H₁₅IN₂O₇S₂ 
• 757951-80-7 5-amino-7-benzyloxy-1-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester 
• 757951-77-2 N-methanesulfonyl-2-benzyloxy-6-iodo-4-nitroaniline 
• 757951-78-3 2-iodo-4-nitro-6-(phenylmethoxy)benzenamine 
• 174868-46-3 methyl 4-benzyloxy-3,7-dihydro-6-(methoxycarbonyl)-6H-pyrrolo<3,2-f>quinoline-2-carboxylate 
• 100-39-0 benzyl bromide 

Relevant academic research and scientific papers

New synthetic method for indole-2-carboxylate and its application to the total synthesis of duocarmycin SA

(Equation Presented) The sequential coupling and cyclization reactions between aryl halides and methyl propiolate were investigated. The electron-withdrawing groups on the aromatic ring are essential for producing the methyl indole-2-carboxylate derivativ