75813-16-0

Basic information

• Product Name: C₂₈H₄₆N₄O₂
• Synonyms: C₂₈H₄₆N₄O₂
• CAS NO: 75813-16-0
• Molecular Weight: 470.699
• Mol File: 75813-16-0.mol

Chemical Properties

• CAS DataBase Reference: C₂₈H₄₆N₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₄₆N₄O₂(75813-16-0)
• EPA Substance Registry System: C₂₈H₄₆N₄O₂(75813-16-0)

Safety Data

• Hazardous Substances Data: 75813-16-0(Hazardous Substances Data)

Upstream product

• 625-04-7 4-amino-4-methylpentan-2-one 
• 141-79-7 4-methyl-pent-3-en-2-one 
• 67-66-3 chloroform 
• 75813-07-9 N⁴-{3-[(3-Amino-1,3-dimethyl-butylamino)-methyl]-benzyl}-2-methyl-pentane-2,4-diamine 
• 67-64-1 acetone 

Relevant articles and documents

Synthesis of Hexahydro-3,3,5,5,7-pentaalkyl-2H-1,4-diazepin-2-ones from 1,3-Diamines and Ketones

A new method for preparing mono- and bis(hexahydro-3,3,5,5,7-pentaalkyl-2H-1,4-diazepin-2-ones) is reported (Schemes I and II).The key step of this synthesis is the final one in which a 1,3-diamine is reacted with a ketone in the presence of sodium hydroxide, chloroform, and a phase-transfer catalyst (PTC).Bis(hexahydro-3,3,5,5,7-pentaalkyl-2H-1,4-diazepin-2-ones) are isolated as a mixture of diastereomers.Of these bis compounds, diastereomers of 1,1'-(1,2-ethanediyl)bis(hexahydro-3,3,5,5,7-pentamethyl-2H-1,4-diazepin-2-one) (5a) can be readily separated by a fractional recrystallization, or their diastereomeric distributions can be measured by 13C NMR.