75853-35-9

Upstream product

• 250636-76-1 N-tert-butoxycarbonylglycyl-glycyl-L-tyrosine methyl ester 
• 4530-20-5 BOC-glycine 
• 31972-52-8 Boc-Gly-Gly-OH 
• 53487-98-2 N-tert-butoxycarbonyl glycyl glycine methyl ester 

Downstream Products

• 250636-78-3 N-tert-butoxycarbonylglycyl-glycyl-L-tyrosyl-L-prolyl-L-leucyl-L-isoleucyl-L-leucine methyl ester 
• 1026264-10-7 Boc-Gly-Gly-Tyr-Pro-Leu-Ile-Leu-OPNP 

Relevant academic research and scientific papers

Recyclable hypervalent-iodine-mediated solid-phase peptide synthesis and cyclic peptide synthesis

The system of the hypervalent iodine(III) reagent FPID and (4-MeOC6H4)3P was successfully applied to solid-phase peptide synthesis and cyclic peptide synthesis. Four peptides with biological activities were synthesized through SPPS and the bioactive cyclic heptapeptide pseudostellarin D was obtained via solution-phase peptide synthesis. It is worth noting that FPID can be readily regenerated after the peptide coupling reaction.

Synthesis and biological evaluation of Pseudostellarin D

Pseudostellarin D, a natural cyclic heptapeptide, was successfully synthesized and characterized by IR, 1H NMR, 13C NMR, FABMS and elemental analysis. The synthesized compound was evaluated for antibacterial, antifungal, anti-inflammatory and anthelmintic activities.