75889-61-1Relevant academic research and scientific papers
Organic Phosphorus Compounds. 1. 4-(Benzothiazol-2-yl)benzylphosphonate as Potent Calcium Antagonistic Vasodilator
Yoshino, Kohichiro,Kohno, Toshihiko,Uno, Toshio,Morita, Tominori,Tsukamoto, Goro
, p. 820 - 825 (2007/10/02)
A series of 4-(benzothiazol-2-yl)benzylphosphonic acid dialkyl ester were synthesized and evaluated for coronary vasodilatory activity by Langendorff's method in the isolated guinea pig heart. Many of the phosphonic acid dialkyl esters exhibited vasodilat
Calcium-antagonistic composition
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, (2008/06/13)
A phosphonic acid ester of the formula: STR1 and R is a lower alkyl, exhibits a calcium-antagonistic activity. Pharmaceutical compositions containing the same are useful in prophylaxis and treatment of ischemic heart diseases such as angina pectoris, myoc
