75889-62-2

Basic information

• Product Name: 2-[4-(DIETHOXYPHOSPHORYLMETHYL)PHENYL]BENZOTHIAZOLE
• Synonyms: 2-[4-(DIETHOXYPHOSPHORYLMETHYL)PHENYL]BENZOTHIAZOLE;Fostedil;fosfedil;[[4-(Benzothiazol-2-yl)phenyl]methyl]phosphonic acid diethyl ester;Abbott-53986;KB-944
• CAS NO: 75889-62-2
• Molecular Formula: C₁₈H₂₀NO₃PS
• Molecular Weight: 393.393861
• Mol File: 75889-62-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: 96.5°C
• Boiling Point: 512.1°C at 760 mmHg
• Flash Point: 263.5°C
• Appearance: /solid
• Density: 1.243g/cm³
• Vapor Pressure: 4.29E-10mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: 2-[4-(DIETHOXYPHOSPHORYLMETHYL)PHENYL]BENZOTHIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(DIETHOXYPHOSPHORYLMETHYL)PHENYL]BENZOTHIAZOLE(75889-62-2)
• EPA Substance Registry System: 2-[4-(DIETHOXYPHOSPHORYLMETHYL)PHENYL]BENZOTHIAZOLE(75889-62-2)

Safety Data

• Hazardous Substances Data: 75889-62-2(Hazardous Substances Data)

Usage

Uses

Vasodilator (calcium channel blocker).

InChI:InChI=1/C18H20NO3PS/c1-3-21-23(20,22-4-2)13-14-9-11-15(12-10-14)18-19-16-7-5-6-8-17(16)24-18/h5-12H,3-4,13H2,1-2H3

Upstream product

• 137-07-5 2-amino-benzenethiol 
• 104-87-0 4-methyl-benzaldehyde 
• 24239-18-7 2-<4-(bromomethyl)phenyl>benzothiazole 
• 78-40-0 triethyl phosphate 
• 56108-06-6 p-toluimidic acid methyl ester 
• 16112-21-3 2-(4-methylphenyl)-1,3-benzothiazole 
• 122-52-1 triethyl phosphite 
• 17448-38-3 Diethyl Isopropyl Phosphite 

Downstream Products

• 1326307-81-6 (E)-4-(4-(benzo[d]thiazol-2-yl)styryl)-N,N-bis(4-bromophenyl)aniline 
• 1326307-82-7 (E)-2-(4-(2-(2,5-dibromothiophen-3-yl)vinyl)phenyl)benzo[d]thiazole 
• 1228700-03-5 [4-[2-[7-[2-(4-benzothiazol-2-ylphenyl)vinyl]-9,9-didecyl-9H-fluoren-2-yl]vinyl]phenyl]dibutylamine 
• 128766-93-8 Ethyl 3-Nitroxypropyl 4-(Benzothiazol-2-yl)benzylphosphonate 
• 128766-92-7 (4-Benzothiazol-2-yl-benzyl)-phosphonic acid ethyl ester 2-nitrooxy-ethyl ester 
• 128766-95-0 Ethyl 3-Acetoxypropyl 4-(Benzothiazol-2-yl)benzylphosphonate 
• 128766-91-6 (4-Benzothiazol-2-yl-benzyl)-phosphonic acid 2-ethoxy-ethyl ester ethyl ester 
• 128766-88-1 (4-Benzothiazol-2-yl-benzyl)-phosphonic acid ethyl ester 2,2,2-trifluoro-ethyl ester 
• 128787-88-2 (4-Benzothiazol-2-yl-benzyl)-phosphonic acid 2-dimethylamino-ethyl ester ethyl ester 
• 128766-87-0 (4-Benzothiazol-2-yl-benzyl)-phosphonic acid 3-bromo-propyl ester ethyl ester 
• 128766-90-5 Ethyl 3-Hydroxypropyl 4-(Benzothiazol-2-yl)benzylphosphonate 
• 128766-83-6 (4-Benzothiazol-2-yl-benzyl)-phosphonic acid 2,2-dimethyl-propyl ester ethyl ester 
• 128766-89-2 (4-Benzothiazol-2-yl-benzyl)-phosphonic acid ethyl ester 2-hydroxy-ethyl ester 
• 128766-86-9 (4-Benzothiazol-2-yl-benzyl)-phosphonic acid 2-bromo-ethyl ester ethyl ester 

Relevant articles and documents

Benzothiazole derivatives containing different electron acceptors exhibiting totally different data-storage performances

Two small conjugated molecules BTVCz-NO2 and BTVCz, each incorporating an electron-donating carbazole group and a medium electron-withdrawing benzothiazole group, were both successfully designed and synthesized. Molecule BTVCz-NO2 is

Synthesis and photovoltaic properties of two-dimensional D-A copolymers with conjugated side chains

Four novel two-dimensional (2D) donor-acceptor (D-A) type copolymers with different conjugated side chains, P1, P2, P3, and P4 (see Fig. 1), are designed and synthesized for the application as donor materials in polymer solar cells (PSCs). To the best of

Synthesis of fostedil (diethyl 4-(2-benzothiazolyl)benzylphosphonate) from N-acylimidates

Fostedil (diethyl 4-(benzothiazol-2-yl) benzylphosphonate) 7 has been synthesized efficiently by treatment of 2-(4-bromomethylphenyl) benzothiazole 6 with triethylphosphite. The latter (6) has been prepared by bromation of benzothiazole 3c. N-acylimidates 1(a-d) react with 2-aminobenzenethiol 2 to lead to the corresponding benzothiazoles 3(a-d) after elimination of primary amide 5. The structure of these products have been unequivocally confirmed by means of IR, 1H, 13C, and 31P NMR spectroscopy and mass spectra.