75945-91-4

Usage

Uses

Used in Pharmaceutical Research and Development:
4-OXO-1-PHENYLCYCLOHEXANECARBOXYLIC ACID is utilized as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs due to its unique chemical structure and properties.
Used in Anti-inflammatory and Analgesic Applications:
In the medical field, 4-OXO-1-PHENYLCYCLOHEXANECARBOXYLIC ACID is studied for its potential as an anti-inflammatory and analgesic agent, offering a new avenue for the treatment of pain and inflammation.
Used in Neurodegenerative Disease Treatment:
4-OXO-1-PHENYLCYCLOHEXANECARBOXYLIC ACID is being explored for its role in the treatment of neurodegenerative diseases, indicating its potential to mitigate the effects of such conditions and improve patient outcomes.
Used in Organic Synthesis:
As a carboxylic acid derivative, 4-OXO-1-PHENYLCYCLOHEXANECARBOXYLIC ACID is employed in organic synthesis for the creation of a wide range of chemical compounds, highlighting its versatility and importance in the chemical industry.

InChI:InChI=1/C13H14O3/c14-11-6-8-13(9-7-11,12(15)16)10-4-2-1-3-5-10/h1-5H,6-9H2,(H,15,16)

Upstream product

• 51509-99-0 8-Phenyl-1,4-dioxaspiro<4.5>decan-8-carbonsaeure 
• 292638-85-8 acrylic acid methyl ester 
• 101-41-7 benzeneacetic acid methyl ester 
• 951314-25-3 dimethyl 4-oxo-1-phenyl-1,3-cyclohexanedicarboxylate 
• 25115-74-6 4-cyano-4-phenylcyclohexanone 
• 374794-40-8 dimethyl 4-oxo-1-phenyl-1,3-cyclohexanedicarboxylate 
• 140-29-4 phenylacetonitrile 
• 3592-25-4 1,5-dichloropentan-3-one 
• 108-24-7 acetic anhydride 
• 75945-89-0 2.2-Bis-β-chlorethyl-1.3-dioxolan 
• 51509-98-9 8-Phenyl-1,4-dioxaspiro<4.5>decan-8-carbonitril 

Downstream Products

• 5441-44-1 4-hydroxyimino-1-phenyl-cyclohexanecarboxylic acid 
• 374819-28-0 4-oxo-1-phenyl-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}cyclohexanecarboxamide 
• 374819-29-1 (RS)-4-oxo-1-phenyl-N-{1-[3,5-bis(trifluoromethyl)phenyl]ethyl}cyclohexanecarboxamide 
• 95261-39-5 4-amino-4-phenylcyclohexan-1-one 
• 75945-90-3 4-Oxo-1-phenyl-cyclohexancarbonsaeuremethylester 
• 374794-41-9 4-Oxo-1-phenylcyclohexylamine Hydrochloride 
• 374819-27-9 3,5-bis(trifluoromethyl)phenylmethyl 4-oxo-1-phenylcyclohexanecarboxylate 
• 75945-93-6 (cis-4-Methylamino-1-phenyl)-cyclohexancarbonsaeuremethylester 
• 75945-92-5 4-Methylamino-1-phenyl-cyclohexancarbonsaeuremethylester 
• 75945-94-7 4-Benzylamino-1-phenyl-cyclohexancarbonsaeuremethylester 
• 75945-95-8 2-Benzyl-4-phenyl-2-azabicyclo<2.2.2>octan-3-on 
• 75945-96-9 2-Benzyl-4-phenyl-2-azabicyclo<2.2.2>octan 

Relevant academic research and scientific papers

Cyclohexyl derivatives and their use as therapeutic agents

The present invention relates compounds of the formula (I): wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of: (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k), (l) and R1, R2, R3, R4, R5, R6, R7, R13, R14, R15, R16, R?17, R18, R19, R21a and R21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.

Cyclohexane derivatives and their use as therapeutic agents

The present invention relates compounds of formula (I), wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of formulae: (a), (b), (c), (d), and (e); and R1, R2, R3, R4, R5, R6, R7, R13, R14, R15, R16, R17, R21a and R21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.

4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists I.

A series of novel 4,4-disubstituted cyclohexylamine based NK(1) antagonists is described. The effect of changes to the C(1)-C(4) relative stereochemistry on the cyclohexane ring and replacements for the flexible linker are discussed, leading to the identification of compounds with high affinity and good in vivo duration of action.

Arylcycloalkane carboxylic esters, their use, pharmaceutical compositions and preparation

PCT No. PCT/SE97/01310 Sec. 371 Date Apr. 12, 1999 Sec. 102(e) Date Apr. 12, 1999 PCT Filed Jul. 23, 1997 PCT Pub. No. WO98/04517 PCT Pub. Date Feb. 5, 1998This invention relates to the use of 2-(diisopropylamino)-ethyl-1-phenyl-cyclopentane-carboxylate or 2-(diisopropylamino)-ethyl-1-phenyl-cyclohexane-carboxylate, or a pharmaceutically accceptable salt thereof, for treatment of urinary incontinence or irritable bowel syndrome (IBS).

Phenyl-1,2,3,4-tetrahydrocarbazoles and use thereof

This application relates to phenyl-substituted 1,2,3,4-tetrahydrocarbazoles and to their use as anti-depressant agents useful in the treatment of mental depression of either endogenous or reactive nature.

Synthesis and Reactivity of 4-Phenylisoquinuclidines

Several approaches to the synthesis of the 2-alkyl-4-phenylisoquinuclidines 14 and 15, the 3,4-diphenylisoquinuclidines 22-24 and of 6-oxo-4-phenyl-3-isoquinuclidone (43) are described.The structure of the products of hydrolysis of 7-phenyl-1,4-dioxaspirodecanecarboxamide (36) were determined by spectroscopy and degradative reactions.