75945-90-3

Basic information

• Product Name: Methyl 4-oxo-1-phenylcyclohexanecarboxylate
• Synonyms: Methyl 4-oxo-1-phenylcyclohexanecarboxylate;4-Methoxycarbonyl-4-phenylcyclohexanone
• CAS NO: 75945-90-3
• Molecular Formula: C₁₄H₁₆O₃
• Molecular Weight: 232.28
• Product Categories: Heterocyclic Compounds
• Mol File: 75945-90-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 348.336 °C at 760 mmHg
• Flash Point: 152.881 °C
• Appearance: /
• Density: 1.143 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.533
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Methyl 4-oxo-1-phenylcyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-oxo-1-phenylcyclohexanecarboxylate(75945-90-3)
• EPA Substance Registry System: Methyl 4-oxo-1-phenylcyclohexanecarboxylate(75945-90-3)

Safety Data

• Hazardous Substances Data: 75945-90-3(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 16, p. 443, 1951 DOI: 10.1021/jo01143a017

InChI:InChI=1/C14H16O3/c1-17-13(16)14(9-7-12(15)8-10-14)11-5-3-2-4-6-11/h2-6H,7-10H2,1H3

Upstream product

• 67-56-1 methanol 
• 75945-91-4 4-oxo-1-phenylcyclohexanecarboxylic acid 
• 7647-01-0 hydrogenchloride 
• 25115-74-6 4-cyano-4-phenylcyclohexanone 
• 74-88-4 methyl iodide 
• 186581-53-3 diazomethane 
• 75945-89-0 2.2-Bis-β-chlorethyl-1.3-dioxolan 
• 140-29-4 phenylacetonitrile 
• 51509-98-9 8-Phenyl-1,4-dioxaspiro<4.5>decan-8-carbonitril 
• 3592-25-4 1,5-dichloropentan-3-one 
• 51509-99-0 8-Phenyl-1,4-dioxaspiro<4.5>decan-8-carbonsaeure 

Downstream Products

• 1056990-57-8 methyl 4-(nitromethylene)-1-phenylcyclohexanecarboxylate 
• 63383-74-4 2-Methyl-4-phenyl-2-azabicyclo<2.2.2>octan 
• 75945-94-7 4-Benzylamino-1-phenyl-cyclohexancarbonsaeuremethylester 
• 75945-93-6 (cis-4-Methylamino-1-phenyl)-cyclohexancarbonsaeuremethylester 
• 75945-92-5 4-Methylamino-1-phenyl-cyclohexancarbonsaeuremethylester 

Relevant articles and documents

Cyclohexyl derivatives and their use as therapeutic agents

The present invention relates compounds of the formula (I): wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of: (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k), (l) and R1, R2, R3, R4, R5, R6, R7, R13, R14, R15, R16, R?17, R18, R19, R21a and R21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.

Synthesis and Reactivity of 4-Phenylisoquinuclidines

Several approaches to the synthesis of the 2-alkyl-4-phenylisoquinuclidines 14 and 15, the 3,4-diphenylisoquinuclidines 22-24 and of 6-oxo-4-phenyl-3-isoquinuclidone (43) are described.The structure of the products of hydrolysis of 7-phenyl-1,4-dioxaspirodecanecarboxamide (36) were determined by spectroscopy and degradative reactions.