759457-60-8 Usage
General Description
1-[(1S)-Phenylethyl]piperazine is a chemical compound that belongs to the class of piperazine derivatives. It is a psychoactive drug and has been studied for its potential use in the treatment of central nervous system disorders. The compound has a phenylethyl group attached to the piperazine ring, and the stereochemistry of the phenylethyl group is specified as (1S), indicating its configuration as a chiral molecule. 1-[(1S)-Phenylethyl]piperazine has been investigated for its effects on serotonin receptors and has been found to possess some affinity for these receptors. It is considered to be a potential candidate for further research and development as a psychoactive drug.
Check Digit Verification of cas no
The CAS Registry Mumber 759457-60-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,5,9,4,5 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 759457-60:
(8*7)+(7*5)+(6*9)+(5*4)+(4*5)+(3*7)+(2*6)+(1*0)=218
218 % 10 = 8
So 759457-60-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H18N2/c1-11(12-5-3-2-4-6-12)14-9-7-13-8-10-14/h2-6,11,13H,7-10H2,1H3/t11-/m0/s1
759457-60-8Relevant articles and documents
Synthesis of Enantiopure Piperazines via Asymmetric Lithiation-Trapping of N-Boc Piperazines: Unexpected Role of the Electrophile and Distal N-Substituent
Firth, James D.,O'Brien, Peter,Ferris, Leigh
, p. 651 - 659 (2016/01/29)
A new method for the synthesis of enantiopure α-substituted piperazines via direct functionalization of the intact piperazine ring is described. The approach utilizes the asymmetric lithiation-substitution of an α-methylbenzyl-functionalized N-Boc piperaz
Urotensin II receptor antagonists
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Page/Page column 58, (2009/01/24)
This invention is directed to a compound of Formula (I): and forms thereof, wherein A, B, E, G, X and L2 are as defined herein and their use as urotensin II receptor antagonists.
Aralkyl-ketone piperazine derivatives and their uses as new antalgic or ataractic agent
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Page/Page column 13, (2008/06/13)
Arylalkyl ketone piperazine derivatives of the formula: and pharmaceutical compositions comprising the same. Also dislcosed are methods for using the compounds as analgesic and sedative agents. The compounds of the present invention have good analgesic and sedative activities but few side effects.
