75957-53-8

Basic information

• Product Name: Boc-Val-Tyr-OBzl
• Synonyms: (S)-benzyl 2-((S)-2-(tert-butoxycarbonylamino)-3-methylbutanamido)-3-(4-hydroxyphenyl)propanoate;REF DUPL: Boc-Val-Tyr-OBzl
• CAS NO: 75957-53-8
• Molecular Formula: C₂₆H₃₄N₂O₆
• Molecular Weight: 470.563
• Mol File: 75957-53-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 259 °C at 760 mmHg
• Flash Point: 110.4 °C
• Appearance: /
• Density: 1.484 g/cm³
• CAS DataBase Reference: Boc-Val-Tyr-OBzl(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-Val-Tyr-OBzl(75957-53-8)
• EPA Substance Registry System: Boc-Val-Tyr-OBzl(75957-53-8)

Safety Data

• Hazardous Substances Data: 75957-53-8(Hazardous Substances Data)

Usage

General Description

Boc-Val-Tyr-OBzl is a chemical compound with the Boc protecting group on the valine amino acid, and the O-benzyl ester protecting group on the tyrosine amino acid. It is commonly used in peptide synthesis as a building block for creating custom peptide sequences. The Boc protecting group helps to prevent unwanted side reactions during peptide assembly, while the O-benzyl ester group can be removed under milder conditions compared to other common protecting groups, making it a versatile and valuable component in peptide synthesis. Boc-Val-Tyr-OBzl is also used in research and pharmaceutical applications for studying biological processes and developing new drugs.

Upstream product

• 13734-41-3 t-Boc-L-valine 
• 53587-11-4 L-tyrosine benzyl ester p-toluenesulfonate 
• 3392-12-9 Boc-Val-ONSu 
• 42406-77-9 L-tyrosine benzyl ester 

Downstream Products

• 3061-91-4 L-valyl-L-tyrosine 
• 80621-99-4 H-Val-Tyr-OBzl 
• 80622-00-0 H-Val-Tyr-OBzl*TFA 
• 180078-19-7 5-bromopentanoyl-L-valinyl-L-tyrosine benzyl ester 
• 437754-02-4 4-bromobutyryl-L-valinyl-L-tyrosine benzyl ester 
• 180078-21-1 9S-isopropyl-7,10-dioxo-2-oxa-8,11-diaza-bicyclo[12.2.2]octadeca-1⁽¹⁷⁾,14⁽¹⁸⁾,15-triene-12S-carboxylic acid benzyl ester 
• 180078-22-2 10S-isopropyl-8,11-dioxo-2-oxa-9,12-diaza-bicyclo[13.2.2]nonadeca-1⁽¹⁸⁾,15⁽¹⁹⁾,16-triene-13S-carboxylic acid benzyl ester 
• 180078-20-0 6-bromohexanoyl-L-valinyl-L-tyrosine benzyl ester 
• 437754-03-5 (S)-3-(4-Hydroxy-phenyl)-2-[(S)-2-(6-iodo-hexanoylamino)-3-methyl-butyrylamino]-propionic acid benzyl ester 
• 75957-54-9 N^α-t-butoxycarbonyl-β-benzyl-L-aspartyl-L-valyl-L-tyrosine benzyl ester 
• 95548-52-0 2>-thymopentin (Arg-Pro-Asp-Val-Tyr) 
• 271600-76-1 Z₃ArgGlyAsp(OBzl)ValTyrOBzl 
• 271600-77-2 benzyl ester of N^α,N^G,N^G-tribenzyloxycarbonyl-argynyl-N-prolyl-β-benzylaspartyl-valyl-tyrosine 
• 77456-95-2 N^α-tert-butoxycarbonylvalyltyrosine 

Relevant articles and documents

Sequential Intermolecular Radical Addition and Reductive Radical Cyclization of Tyrosine and Phenylalanine Derivatives with Alkenes via Photoinduced Decarboxylation: Access to Ring-Constrained γ-Amino Acids

Sequential radical addition to alkenes and reductive radical cyclization of phenylalanine and tyrosine derivatives via photoinduced decarboxylation furnished ring-constrained γ-amino acids under mild conditions. A variety of alkenes such as acrylamides and acrylic esters could be employed in the photoinduced radical cascade cyclization. The yields of the ring-constrained γ-amino acids are dependent on the electron-accepting ability and steric hindrance of the alkene used. The proposed sequential reaction can also be applied for direct tethering of dipeptides to yield unique ring-constrained tetrapeptides.

Conformationally constrained macrocycles that mimic tripeptide β-strands in water and aprotic solvents

The β-strand conformation is unknown for short peptides in aqueous solution, yet it is a fundamental building block in proteins and the crucial recognition motif for proteolytic enzymes that enable formation and turnover of all proteins. To create a gener

PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST

Short-chain peptide derivatives acting on angiotensin IV receptor at low concentrations. Because of agonistically acting on angiotensin IV receptor, the novel peptide derivatives of the present invention represented by the following formula (1) are useful as remedies for various diseases in which angiotensin IV participates: