75989-44-5

Upstream product

• 56-86-0 L-glutamic acid 
• 21461-84-7 (2S)-tetrahydro-5-oxofuran-2-carboxylic acid 
• 1589-82-8 phenylmagnesium bromide 
• 54848-33-8 (S)-tetrahydro-5-oxo-2-furancarbonyl chloride 
• 6921-34-2 benzylmagnesium chloride 

Downstream Products

• 125225-51-6 (5S,1'R)-5-(1'-hydroxy-2'-phenylethyl)dihydrofuran-2(3H)-one 
• 125225-52-7 (5S,1'S)-5-(1'-hydroxy-2'-phenylethyl)dihydrofuran-2(3H)-one 
• 145761-25-7 (5S,1'R)-5-(1'-bromo-2'-phenylethyl)dihydrofuran-2(3H)-one 
• 138381-24-5 (S,E)-5-styryldihydrofuran-2(3H)-one 
• 137038-63-2 deux références: JFP452-1 et JFP456b 
• 133333-27-4 tert-butyl (1S)-1-[(2S)-5-oxotetrahydrofuran-2-yl]-2-phenylethylcarbamate 
• 145761-24-6 (5S,1'S)-5-(1'-methanesulfonyloxy-2'-phenylethyl)dihydrofuran-2(3H)-one 

Relevant academic research and scientific papers

A formal stereoselective synthesis of a hydroxyethylene dipeptide isostere

4-Hydroxy-5-amino-6-phenyl-4-hexanolide has been synthesized under its cyclized form (lactone 5) from a very inexpensive chiral starting material, L-glutamic acid. The key steps were an original reduction of carbonyl of a ketone with n-Bu3SnH i

Studies of HIV-1 protease inhibitors. II. Incorporation of four types of hydroxyethylene dipeptide isosteres at the scissile site of substrate sequences

Human immunodeficiency virus type 1 (HIV-1) protease inhibitors containing four types of hydroxyethylene dipeptide isosteres were designed and synthesized. These inhibitors consist of eight stereoisomers of phenylalanylproline (Phe-Ψ[H.E.]-Pro), four ster

LATERAL ROOT INDUCING COMPOUNDS FROM THE BACTERIUM ERWINIA QUERCINA: ISOLATION, STRUCTURE AND SYNTHESIS

The structures lateral root inducing compounds produced in culture by the bacterium Erwinia quercina were shown to be two diastereomers of 4,5-dihydroxy-6-phenylhexanoic acid.All four chiral isomers of the active structure were synthesized.