76-36-8

Basic information

• Product Name: 2,2,3-trichlorobutyraldehyde
• Synonyms: 2,2,3-trichlorobutyraldehyde;2,2,3-Trichlorobutanal;Anhydr butylchloral;Butyrchloral;Crotonchloral;α,α,β-Trichloro-n-butylaldehyde;a,a,b-Trichloro-n-butyraldehyde
• CAS NO: 76-36-8
• Molecular Formula: C₄H₅Cl₃O
• Molecular Weight: 175.4409
• EINECS: 200-953-4
• Mol File: 76-36-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: bp760 164.5-165.5°; bp25 57-60°
• Flash Point: 64.6°C
• Appearance: /
• Density: d420 1.3956
• Vapor Pressure: 1.91mmHg at 25°C
• Refractive Index: nD20 1.47554
• CAS DataBase Reference: 2,2,3-trichlorobutyraldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,3-trichlorobutyraldehyde(76-36-8)
• EPA Substance Registry System: 2,2,3-trichlorobutyraldehyde(76-36-8)

Safety Data

• Hazardous Substances Data: 76-36-8(Hazardous Substances Data)

Usage

General Description

2,2,3-trichlorobutyraldehyde is a chemical compound with the molecular formula C4H4Cl3O. It is a colorless to pale yellow liquid with a pungent odor and is used mainly as an intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds. 2,2,3-trichlorobutyraldehyde is classified as an aldehyde, which means it contains a carbonyl group (C=O) bonded to at least one hydrogen atom. 2,2,3-trichlorobutyraldehyde is also known for its use as a reactive intermediate in the synthesis of various organic compounds. Its chemical reactivity and potential health hazards make it important for proper handling and storage in industrial and laboratory settings.

Upstream product

• 75-07-0 acetaldehyde 
• 123-73-9 crotonaldehyde 
• 16419-55-9 2,4-dimethyl-6-(1,1,2-trichloro-propyl)-[1,3,5]trioxane 
• 53175-28-3 2-chloro-2-butenal 
• 7782-50-5 chlorine 
• 56-23-5 tetrachloromethane 
• 76-40-4 2,2,3-tri-chlorobutane-1,1-diol 
• 55775-41-2 2,3-dichlorobutyraldehyde 
• 7732-18-5 water 
• 7664-93-9 sulfuric acid 
• 7647-01-0 hydrogenchloride 
• 123-63-7 paracetaldehyde 
• 108-24-7 acetic anhydride 

Downstream Products

• 42049-32-1 2,2,3-Trichlorbutyliden-N,N'-bis-(S-benzyl-thiocarbamat) 
• 123-73-9 crotonaldehyde 
• 6117-91-5 (E/Z)-2-buten-1-ol 
• 123-72-8 butyraldehyde 
• 71-36-3 butan-1-ol 
• 1092453-06-9 C₁₀H₁₆Cl₃N 
• 1092453-07-0 C₁₁H₁₂Cl₃N 
• 74544-16-4 2,4-dichlorophenyl (2,3,3-trichloro-4-hydroxy-5-imidazol-1-yl)-pent-5-yl ketone 
• 73144-12-4 N-benzoyl-N'-(2,2,3-trichlorobutylidene)hydrazine 
• 74-85-1 ethene 
• 5344-55-8 2,2,3-trichloro-butyric acid 
• 76-40-4 2,2,3-tri-chlorobutane-1,1-diol 
• 53993-41-2 (Z)-2-Chloro-but-2-enoic acid 
• 25663-23-4 N-(4-{[(Ξ)-1-(2,4-diamino-pteridin-6-yl)-ethyl]-methyl-amino}-benzoyl)-L-glutamic acid 

Relevant articles and documents

Synthesis and reactivity of novel α,α,β- and α,α,δ-trichlorinated imines

A variety of different N-(2,2,3-trichloropropylidene)amines, N-(2,2,3-trichlorobutylidene)amines, and N-(2,2,5-trichloropentylidene)amines were synthesized for the first time, and their reactivity with regard to hydride reagents was investigated. In this way, N-(2,2,5-trichloropentylidene)amines were evaluated as substrates for the synthesis of piperidines, and N-(2,2,3-trichloropropylidene)amines and N-(2,2,3-trichlorobutylidene)amines were reduced efficiently into the corresponding novel β,β,γ- trichloroamines by means of sodium cyanoborohydride in methanol in the presence of acetic acid. Furthermore, N-(2,2,3-trichloropropylidene)amines were transformed into 2-(chloromethyl)aziridines by lithium aluminium hydride in Et2O, and N-(2,2,5-trichloropentylidene)acetamide was used for the first time as a suitable substrate for the addition of oxygen, nitrogen, and sulfur nucleophiles in good yields. Georg Thieme Verlag Stuttgart.