76106-72-4

Upstream product

• 3033-92-9 1-(3-hydroxyphenyl)-3-phenyl-2-propen-1-one 
• 108-95-2 phenol 
• 3033-92-9 (E)-1-(3-hydroxyphenyl)-3-phenylprop-2-en-1-one 
• 121-71-1 3-Hydroxyacetophenone 
• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 100-52-7 benzaldehyde 
• 22966-24-1 (E)-1-(3-methoxyphenyl)-3-phenylprop-2-en-1-one 

Downstream Products

• 1274878-97-5 4-oxido-4-(2-{[1-oxo-3-phenyl-2-(pyridin-3-yl)-1H-inden-6-yl]oxy}ethyl)morpholin-4-ium 
• 1274878-98-6 4-oxido-4-(2-{[2-(1-oxidopyridin-1-ium-3-yl)-1-oxo-3-phenyl-1H-inden-6-yl]oxy}ethyl)morpholin-4-ium 
• 1092564-96-9 6-acetoxy-2-bromo-3-phenylinden-1-one 
• 1092564-94-7 2-bromo-6-hydroxy-3-phenylinden-1-one 
• 1274877-34-7 6-(2-morpholinoethoxy)-2-bromo-3-phenyl-1H-inden-1-one 
• 1274877-35-8 6-(2-morpholinoethoxy)-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one 
• 76106-74-6 6-methoxy-3-phenyl-2,3-dihydro-1H-inden-1-one 
• 1274878-94-2 1-methyl-3-{6-[2-(morpholin-4-yl)ethoxy]-1-oxo-3-phenyl-1H-inden-2-yl}pyridin-1-ium iodide 

Relevant academic research and scientific papers

NOVEL COMPOUND AND METHOD OF PRODUCING THAT COMPOUND

PROBLEM TO BE SOLVED: To provide a novel polyfunctional epoxy compound, and a method of producing the compound. SOLUTION: The invention provides a compound represented by the formula (I) in the figure, where X are each independently O or S; and R are each independently H, halogen, NO2, CN, an alkyl group, an aryl group, or the like. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPO&INPIT

Indenone Derivative and Pharmaceutical Composition Comprising Same

An indenone derivative of formula (1) is effective in enhancing the activity of osteoblastic cells and inhibiting bone resorption by osteoclastic cells, and a pharmaceutical composition comprising the indenone derivative or a pharmaceutically acceptable salt thereof is useful for preventing or treating bone diseases such as osteoporosis.

INDENONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

An indenone derivative of formula (1) is effective in enhancing the activity of osteoblastic cells and inhibiting bone resorption by osteoclastic cells, and a pharmaceutical composition comprising the indenone derivative or a pharmaceutically acceptable salt thereof is useful for preventing or treating bone diseases such as osteoporosis.

Facile synthesis of alkyl 1-oxo-3-phenyl-1H-indene-2-earboxylate through palladium-catalyzed carboalkoxylation from 2-bromo-3-phenylinden-1-ones

Palladium-catalyzed carboalkoxylation of 2-bromo-3-phenylindenones in various alcoholic solvents afforded diverse alkyl 1-oxo-3-phenyl-1H-indene-2- carboxylates in high yields. Copyright

Reactive Annulenones: A Comparative Study

Two new and hitherto elusive annulenones, 3-phenylcyclopentadienone and bicycloocta-1(5),3,6-triene-2,8-dione, are reported.Their lifetimes and reactivities have been studied in comparison with those of the related annulenones cyclopentadienone and 4-phenylbicycloocta-1(5),3,6-triene-2,8-dione.The influence of structure and substituents on the stabilities of these species has thereby been established.

Intramolecular Alkylation of Phenols. Part 4. Base-catalysed Cyclisation of Phenolic Enones. Scope and Limitations

The phenolic enones (4), (5), (8), (9), and (13) cyclise readily under acidic conditions.However, neither these nor the thio-substituted phenols (11a), (13a), (14a), and (15a) closed under basic conditions.Involvement of unfavourable equilibria is disproved.Comparison is made with related successful cyclisations of the saturated ketone (38) and aldehyde (39).Preliminary results suggest that strict stereo-electronic requirements are necessary for enone ring closure and that these conditions are not met in base-catalysed 5-Endo- and 6-Endo-Trigonal ring closures of the phenols of general type (2; n=0 and n=1).