76144-17-7

Upstream product

• 103841-62-9 (R)-3-Benzylamino-4-chlorocarbonyl-butyric acid methyl ester; hydrochloride 
• 76144-22-4 (R)-3-Amino-pentanedioic acid benzyl ester methyl ester 
• 103883-24-5 (S)-N-benzyl-4-hydroxymethyl-2-azetidinone 
• 103841-67-4 (S)-N-benzyl-4-2'-tetrahydropyranoxymethyl-2-azetidinone 
• 103841-66-3 ethyl (S)-3-benzylamino-4-2'-tetrahydropyranoxybutyrate 
• 76144-15-5 1-benzyl 5-methyl (R)-3-tert-butoxycarbonylaminoglutarate 
• 103841-68-5 (S)-N-benzyl-4-tosyloxymethyl-2-azetidinone 
• 86694-81-7 1-benzyl-4-(mesyloxymethyl)-2-azetidinone 
• 85390-46-1 1-Benzyl-4-(hydroxymethyl)azetidin-2-one 
• 1613229-02-9 C₁₂H₁₄N₂O₂ 
• 78159-38-3 1-Benzyl-4-oxo-azetidine-2-carboxylic acid methyl ester 
• 1613228-93-5 1-benzyl-4-cyanomethyl-β-lactam 
• 85390-48-3 1-Benzyl-4-(iodomethyl)azetidin-2-one 
• 146667-10-9 (3R,2'S) N-(Benzyl)-3-(3'-acetoxy-2'-tert-butyldimethylsilylpropyl)-isoxazolidin-5-one 

Downstream Products

• 76144-18-8 (S)-N-(diphenylmethyloxycarbonyl)methyl-2-azetidinone 
• 80974-44-3 (S)-N-benzyl-4-carboxymethyl-2-azetidinone 
• 76144-20-2 (4R)-4-<3-(Benzyloxycarbonyl)-2-oxopropyl>azetidin-2-one 
• 82290-94-6 (R)-4-3'-diazo-3'-p-nitrobenzyloxycarbonyl-2'-oxopropyl-2-azetidinone 
• 82336-07-0 p-nitrobenzyl (3R,5R)-1-carba-2-oxopenam-3-carboxylate 
• 87727-17-1 (R)-4-3'-p-nitrobenzyloxycarbonyl-2'-oxopropyl-2-azetidinone 
• 103841-73-2 p-nitrobenzyl (5S,2'R)-2-2'-p-nitrobenzyloxycarbonyl-2'-p-nitrobenzyloxycarbonylaminoethylthio-1-carba-2-penem-3-carboxylate 
• 103841-71-0 (R)-4-3'-diphenylmethyloxycarbonyl-3'-p-nitrobenzyloxycarbonyl-2'-oxopropyl-2-azetidinone 
• 76144-21-3 (R)-4-3'-benzyloxycarbonyl-3'-diazo-2'-oxopropyl-2-azetidinone 
• 76189-53-2 benzyl (3R,5R)-1-carba-2-oxopenam-3-carboxylate 

Relevant academic research and scientific papers

Efficient synthesis of highly enantiopure β-lactam derivatives from biocatalytic transformations of amides and nitriles

Catalyzed by Rhodococcus erythropolis AJ270, a nitrile hydratase and amidase containing microbial strain, under mild conditions, kinetic resolution of racemic amides provides an efficient and scalable route to highly enantioenriched R-4-carboxymethyl-β-la

An approach to carbapenems from α,β-unsaturated sugar lactones

Conjugate addition-rearrangement of N-substituted hydroxylamines to α,β-unsaturated D-lactones provides a short and effective route to 3-substituted isoxazolidin-5-ones. These compounds were converted into 4-substituted azetidin-2-ones via a two-step proc

HIGHLY EFFICIENT OXAZOLONE-DERIVED REAGENTS FOR BETA-LACTAM FORMATION FROM BETA-AMINO ACIDS

Based on a unique leaving ability of 2-oxazolone moiety, highly efficient reagents have been developed for the formation of β-lactam compounds from β-amino acids including a facile preparation of penam, a basic skeleton of penicillins.

SYNTHETIC STUDIES ON OPTICALLY ACTIVE β-LACTAMS. CHIRAL SYNTHESIS OF CARBAPENAM RING SYSTEM STARTING FROM L-ASPARTIC ACID

Benzyl (3R,5R)-1-carba-2-oxopenam-3-carboxylate (12), a useful synthon for β-lactams having carbapenem ring system, was synthesized in optically pure state starting from L-aspartic acid.