76148-78-2Relevant academic research and scientific papers
Synthesis method of beta-ketosulfone compound
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Paragraph 0055-0056; 0067-0070, (2020/05/08)
The invention discloses a synthesis method of a beta-ketosulfone compound, and belongs to the technical field of chemical synthesis. According to the synthesis method, tetrafluoroborate diazonium salt, alkyne and DABCO. (SO2) 2 are subjected to an oxidation bifunctionalization reaction to prepare the beta-ketosulfone compound. The method comprises the following steps: adding DABCO.( SO2) 2, alkyneand tetrafluoroborate diazonium salt which are used as reactants and mesoporous carbon nitride, an organic solvent, water and oxygen which are used as catalysts into a reactor, and stirring for 6-10hours at room temperature under the irradiation of visible light. The method is mild in reaction condition, simple to operate and high in atom economy, and the catalysts can be recycled.
Visible-light-induced direct oxysulfonylation of alkynes with sulfonyl chlorides and HCl
Niu, Tengfei,Jiang, Dingyun,Ni, Bangqing
supporting information, p. 4299 - 4303 (2017/10/12)
A mild, practical and efficient strategy to prepare β-keto sulfones has been developed by visible-light-induced reactions. This reaction involved Ir(dtbbpy)(ppy)2PF6-catalyzed direct functionalization of alkynes with sulfonyl chloride and HCl using air as the oxidant. HCl not only acted as a hydrogen source in the proton transfer process, but also played a vital role in the reaction process.
Visible-light-promoted oxidative difunctionalization of alkenes with sulfonyl chlorides to access β-keto sulfones under aerobic conditions
Niu, Teng-fei,Cheng, Jing,Zhuo, Chang-li,Jiang, Ding-yun,Shu, Xing-ge,Ni, Bang-qing
supporting information, p. 3667 - 3671 (2017/08/22)
A mild, practical and efficient strategy to prepare β-keto sulfones has been developed by visible light promoted reactions. This reaction involves Ir(ppy)2(dtbbpy)PF6 catalyzed direct funcationalization of alkenes with sulfonyl chlorides under mild conditions. Air was used as oxidant without any additives. The transformation affords the corresponding products in moderate to high yields.
An efficient fluorination of β-ketosulfones promoted by a room-temperature ionic liquid at ambient conditions under ultrasound irradiation using Selectfluor F-TEDA-BF4
Heravi, Mohammad Reza Poor
, p. 1399 - 1402 (2011/10/08)
The fluorination reaction involving a β-ketosulfones by Selectfluor was efficiently promoted by the ionic liquid, [Hbim]BF4 (IL) as a reaction medium with methanol as co-solvent at room temperature under ultrasonic irradiation to afford the corresponding mono and difluoro-β-ketosulfones in excellent yields. The advantages of this method include among others the use of a recyclable, non-volatile ionic liquid, which promotes this protocol under room temperature without the requirement of any added catalyst under ultrasonic irradiation.
From phenothiazine to 3-phenyl-1,4-benzothiazine derivatives as inhibitors of the Staphylococcus aureus NorA multidrug efflux pump
Sabatini, Stefano,Kaatz, Glenn W.,Rossolini, Gian Maria,Brandini, David,Fravolini, Arnaldo
experimental part, p. 4321 - 4330 (2009/05/07)
Overexpression of efflux pumps is an important mechanism by which bacteria evade effects of substrate antimicrobial agents and inhibition of such pumps is a promising strategy to circumvent this resistance mechanism. NorA is a Staphylococcus aureus multid
New dyes based on 3-aryl-benzo- and -naphtho-1,4-thiazines
MacKenzie, Neil E.,Thomson, Ronald H.,Greenhalgh, Colin W.
, p. 2923 - 2932 (2007/10/02)
3-Aryl-2H-1,4-benzothiazines have been converted into cyanine dyes by condensing their hydroperchlorates with aldehydes, and into azo-compounds by coupling with reactive diazonium salts. The azo-compounds were also obtained by condensing arylglyoxal hydra
