76160-04-8Relevant academic research and scientific papers
Oxygen-to-Oxygen Silyl Migration of α-Siloxy Sulfoxides and Oxidation-Triggered Allicin Formation
Kelly, Shane S.,Shen, Tun-Li,Xian, Ming
supporting information, p. 3741 - 3745 (2021/05/10)
Oxidation of α-siloxy thioethers leads to the formation of the corresponding sulfoxides as unstable intermediates, which undergo an intramolecular oxygen-to-oxygen silyl migration to break the C-S linkage. This process produces silyl protected sulfenic acids and subsequently thiosulfinates. It was used to develop oxidation-triggered allicin donors.
PREPARATION OF THIOLS USING α-TRIMETHYLSILOXY DERIVATIVES
Harpp, David N.,Kobayashi, Michio
, p. 3975 - 3978 (2007/10/02)
Aliphatic thiols (1) can be prepared under the mildest conditions presently available by desilylation of the appropriate α-trimethylsiloxy sulfide (3).Sulfides 3 are generated by either alkylation of the corresponding alkyl halide or by standard literature methods.
