76172-98-0

Downstream Products

• 76173-00-7 (Z)-2-{(2R,3S)-2-[(2R,3S)-1-((Z)-1-Benzhydryloxycarbonyl-3-hydroxy-2-methyl-propenyl)-4-oxo-3-phenylacetylamino-azetidin-2-yldisulfanyl]-4-oxo-3-phenylacetylamino-azetidin-1-yl}-4-hydroxy-3-methyl-but-2-enoic acid benzhydryl ester 
• 76173-01-8 (Z)-4-Hydroxy-3-methyl-2-((3S,4R)-2-oxo-3-phenylacetylamino-4-p-tolyldisulfanyl-azetidin-1-yl)-but-2-enoic acid benzhydryl ester 
• 76173-02-9 diphenylmethyl 7β-(phenylacetamido)-7α-methoxy-3-methyl-1-oxadethia-3-cephem-4-carboxylate 
• 76231-32-8 (6R,7R)-3-Methyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 76173-03-0 7β-(phenylacetamido)-7α-methoxy-3-methyl-1-oxadethia-3-cephem-4-carboxylic acid 
• 76172-99-1 (Z)-3-Methyl-4-oxo-2-((3S,4R)-2-oxo-3-phenylacetylamino-4-p-tolyldisulfanyl-azetidin-1-yl)-but-2-enoic acid benzhydryl ester 

Relevant academic research and scientific papers

Substituted azetidinone aldehydes

Chemical transformation of the dihydrothiazine ring of a cephalosporin into the dihydrooxazine ring (1-oxacephem) was accomplished utilizing the novel intermediate having the structure STR1 wherein R is an amino-protecting group and R1 is the residue of an ester group which can be removed readily without disrupting the remainder of the molecule as illustrated by phenoxyacetyl as R and benzhydryl as R1.