76173-03-0

Upstream product

• 68314-03-4 (2R,6R,7R)-7-Amino-7-methoxy-3-methylene-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester 
• 76173-00-7 (Z)-2-{(2R,3S)-2-[(2R,3S)-1-((Z)-1-Benzhydryloxycarbonyl-3-hydroxy-2-methyl-propenyl)-4-oxo-3-phenylacetylamino-azetidin-2-yldisulfanyl]-4-oxo-3-phenylacetylamino-azetidin-1-yl}-4-hydroxy-3-methyl-but-2-enoic acid benzhydryl ester 
• 76190-18-6 (Z)-2-{(2R,3S)-2-[(2R,3S)-1-((Z)-1-Benzhydryloxycarbonyl-2-methyl-3-oxo-propenyl)-4-oxo-3-phenylacetylamino-azetidin-2-yldisulfanyl]-4-oxo-3-phenylacetylamino-azetidin-1-yl}-3-methyl-4-oxo-but-2-enoic acid benzhydryl ester 
• 76173-01-8 (Z)-4-Hydroxy-3-methyl-2-((3S,4R)-2-oxo-3-phenylacetylamino-4-p-tolyldisulfanyl-azetidin-1-yl)-but-2-enoic acid benzhydryl ester 
• 76172-99-1 (Z)-3-Methyl-4-oxo-2-((3S,4R)-2-oxo-3-phenylacetylamino-4-p-tolyldisulfanyl-azetidin-1-yl)-but-2-enoic acid benzhydryl ester 
• 76172-98-0 2α-methoxy-3-cephem 
• 76231-32-8 (6R,7R)-3-Methyl-8-oxo-7-phenylacetylamino-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 68402-81-3 diphenylmethyl 7β-benzamido-7α-methoxy-3-<<(1-methyl-1H-yetrazol-5-yl)thio>methyl>-1-oxadethia-3-cephem-4-carboxylate 
• 76173-02-9 diphenylmethyl 7β-(phenylacetamido)-7α-methoxy-3-methyl-1-oxadethia-3-cephem-4-carboxylate 
• 68314-02-3 diphenylmethyl 7β-(phenylacetamido)-7α-methoxy-3-methylene-1-oxadethia-3-cephem-4α-carboxylate 
• 106162-88-3 (2R,6R,7R)-7-Benzoylamino-7-methoxy-3-methylene-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester 
• 103-80-0 phenylacetyl chloride 

Relevant academic research and scientific papers

Synthesis and 3'-Substituent Effects of Some 7α-Methoxy-1-oxacephems on Antibacterial Activity and Alkaline Hydrolysis Rates

Relationships between intrinsic antibacterial activity and β-lactam chemical reactivity of 7β-(phenylacetamido)-7α-methoxy-1-oxacephems with various 3'-substituents (1-9) were studied in order to clarify the effect of the 3'-substituent on the antibacteri

Synthesis of 7β-Amido-7α-methoxy-3-methyl-1-oxacephalosporin

The aldehyde disulfides 2 and 3 were prepared from 2α-methoxy-3-cephem 1 and subsequently reduced to the corresponding alcohols 4.Treatment of these alcohols with mercuric trifluoroacetate resulted in cyclization to 1-oxacepham 5.The epimerization of the