76231-32-8

Upstream product

• 116404-19-4 7-amino-3-methyl-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 103-80-0 phenylacetyl chloride 
• 76173-01-8 (Z)-4-Hydroxy-3-methyl-2-((3S,4R)-2-oxo-3-phenylacetylamino-4-p-tolyldisulfanyl-azetidin-1-yl)-but-2-enoic acid benzhydryl ester 
• 76173-00-7 (Z)-2-{(2R,3S)-2-[(2R,3S)-1-((Z)-1-Benzhydryloxycarbonyl-3-hydroxy-2-methyl-propenyl)-4-oxo-3-phenylacetylamino-azetidin-2-yldisulfanyl]-4-oxo-3-phenylacetylamino-azetidin-1-yl}-4-hydroxy-3-methyl-but-2-enoic acid benzhydryl ester 
• 76190-18-6 (Z)-2-{(2R,3S)-2-[(2R,3S)-1-((Z)-1-Benzhydryloxycarbonyl-2-methyl-3-oxo-propenyl)-4-oxo-3-phenylacetylamino-azetidin-2-yldisulfanyl]-4-oxo-3-phenylacetylamino-azetidin-1-yl}-3-methyl-4-oxo-but-2-enoic acid benzhydryl ester 
• 76172-99-1 (Z)-3-Methyl-4-oxo-2-((3S,4R)-2-oxo-3-phenylacetylamino-4-p-tolyldisulfanyl-azetidin-1-yl)-but-2-enoic acid benzhydryl ester 
• 76172-98-0 2α-methoxy-3-cephem 

Downstream Products

• 76173-02-9 diphenylmethyl 7β-(phenylacetamido)-7α-methoxy-3-methyl-1-oxadethia-3-cephem-4-carboxylate 
• 76173-03-0 7β-(phenylacetamido)-7α-methoxy-3-methyl-1-oxadethia-3-cephem-4-carboxylic acid 

Relevant academic research and scientific papers

Oxacephalosporins

New oxacephalosporin derivative of the general formula: STR1 in which R1 is a protective radical, R2 is either a radical of the general formula: STR2 [in which R5 is hydrogen, alkyl, vinyl, protected carboxyalkyl or a prot

Oxacephalosporins

New oxacephalosporins of the general formula STR1 in which R1 is a protective radical and (a) R4 is a substituted 2-(2-aminothiazol-4-yl)-acetyl radical of which the amine group is protected, or an α-carboxyarylacetyl radical, and R"

Synthesis of 7β-Amido-7α-methoxy-3-methyl-1-oxacephalosporin

The aldehyde disulfides 2 and 3 were prepared from 2α-methoxy-3-cephem 1 and subsequently reduced to the corresponding alcohols 4.Treatment of these alcohols with mercuric trifluoroacetate resulted in cyclization to 1-oxacepham 5.The epimerization of the