76173-02-9Relevant academic research and scientific papers
Synthesis and 3'-Substituent Effects of Some 7α-Methoxy-1-oxacephems on Antibacterial Activity and Alkaline Hydrolysis Rates
Narisada, Masayuki,Nishikawa, Junko,Watanabe, Fumihiko,Terui, Yoshihiro
, p. 514 - 522 (2007/10/02)
Relationships between intrinsic antibacterial activity and β-lactam chemical reactivity of 7β-(phenylacetamido)-7α-methoxy-1-oxacephems with various 3'-substituents (1-9) were studied in order to clarify the effect of the 3'-substituent on the antibacteri
Synthesis of 7β-Amido-7α-methoxy-3-methyl-1-oxacephalosporin
Pfeil, Janice L.,Kukolja, Stjepan,Paquette, Leo A.
, p. 827 - 829 (2007/10/02)
The aldehyde disulfides 2 and 3 were prepared from 2α-methoxy-3-cephem 1 and subsequently reduced to the corresponding alcohols 4.Treatment of these alcohols with mercuric trifluoroacetate resulted in cyclization to 1-oxacepham 5.The epimerization of the
