76231-50-0

Upstream product

• 149312-18-5 1,5-anhydro-4,6-O-benzylidene-3-deoxy-2-O-[(4-methylphenyl)sulfonyl]-D-ribo-hexitol 
• 65-71-4 thymin 
• 164105-30-0 4,6-O-benzylidene-1,5:2,3-dianhydro-D-mannitol 
• 150653-80-8 Methanesulfonic acid (2R,4aR,7R,8aS)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester 
• 150571-95-2 Methanesulfonic acid (2R,4aR,7S,8aS)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester 
• 852235-04-2 (2R,4aR,7S,8aS)-2-Phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol 
• 149312-20-9 1',5'-anhydro-4,6-O-benzylidene-3-deoxy-D-glucitol 
• 150571-93-0 1,5-anhydro-2,3-dideoxy-4,6-O-(phenylmethylene)-D-erythro-hex-1-enitol 

Relevant academic research and scientific papers

Improved synthesis of anhydrohexitol building blocks for oligonucleotide synthesis

The synthesis of the four building blocks used for the preparation of hexitol nucleic acids were optimized. The nucleoside analogues with a purine base moiety are best prepared by a nucleophilic substitution reaction, whereas the pyrimidine nucleosides can best be obtained using Mitsunobu-type conditions. VCH Verlagsgesellschaft mbH, 1997.

Anomeric effect on kinetic acidity: Examples for the oxygen atom of ethers to accelerate abstraction of an α-hydrogen atom

In contrast with general observation, two different types of experiments indicate that the abstraction of α-hydrogen atom of ether having proper conformation is slightly enhanced by the oxygen atom in line with our previous AM1 calculation.