150653-80-8Relevant academic research and scientific papers
The synthesis of modified D- and L-anhydrohexitol nucleosides
Andersen, Marc W.,Daluge, Susan M.,Kerremans, Luk,Herdewijn, Piet
, p. 8147 - 8150 (2007/10/03)
The synthesis and antiviral activities of novel L-isomers 9-13 and modified D-guanine analogs 1d,e of recently reported anhydrohexitol nucleosides 1 are described. An efficient approach to known anhydrohexitol nucleoside precursor 2 from diacetone-D-glucose 3 is also reported.
Anomeric effect on kinetic acidity: Examples for the oxygen atom of ethers to accelerate abstraction of an α-hydrogen atom
Sakakibara, Tohru,Ito, Shinji,Ikegawa, Hiroshi,Matsuo, Ichiro,Seta, Akinori
, p. 3429 - 3432 (2007/10/02)
In contrast with general observation, two different types of experiments indicate that the abstraction of α-hydrogen atom of ether having proper conformation is slightly enhanced by the oxygen atom in line with our previous AM1 calculation.
