76244-65-0

Upstream product

• 1022-46-4 2-phenyl-4H-3,1-benzoxazin-4-one 
• 106-50-3 1,4-phenylenediamine 
• 34280-99-4 3-(4-nitrophenyl)-2-phenylquinazolin-4(3H)-one 
• 118-92-3 anthranilic acid 
• 98-88-4 benzoyl chloride 
• 100-01-6 4-nitro-aniline 

Downstream Products

• 86716-58-7 N-(Imino-{N'-[4-(4-oxo-2-phenyl-4H-quinazolin-3-yl)-phenyl]-guanidino}-methyl)-4-methyl-benzenesulfonamide; hydrochloride 
• 86716-60-1 N-(Imino-{N'-[4-(4-oxo-2-phenyl-4H-quinazolin-3-yl)-phenyl]-guanidino}-methyl)-4-methoxy-benzenesulfonamide; hydrochloride 
• 86716-57-6 N-(Imino-{N'-[4-(4-oxo-2-phenyl-4H-quinazolin-3-yl)-phenyl]-guanidino}-methyl)-benzenesulfonamide; hydrochloride 
• 957217-08-2 C₂₁H₁₇N₃O₃S 
• 133764-71-3 1-(4-Chloro-phenyl)-3-[4-(4-oxo-2-phenyl-4H-quinazolin-3-yl)-phenyl]-thiourea 

Relevant academic research and scientific papers

A synthetic approach and molecular docking study of hybrids of quinazolin-4-ones and thiazolidin-4-ones as anticancer agents

A series of 3-(4-(2-(aryl)-4-oxothiazolidin-3-yl)phenyl-2-phenylquinazolin-4(3H)-one derivatives were synthesized in appreciable yield by using anthranilic acid as a starting material. The structures of synthesized compounds (QT1–QT10) were confirmed on t

Colorimetric studies of heterocyclic monoazo reactive dyes and their dyeing applications on cotton, silk, and wool fibers

Heterocyclic quinazolinone-based hot brand monoazo reactive dyes were obtained by diazotization of 3-(4-aminophenyl)-2-phenylquinazolin-4(3H)-one and coupling with a variety of cyanurated coupling components. All the heterocyclic hot brand monoazo reactiv

Synthesis and anti-inflammatory activity of 2,3-diaryl-4(3H)-quinazolinones

2,3-Diaryl-4(3H)-quinazolinones containing various substituents on diaryl rings have been synthesized and evaluated for their cyclooxygenase-2 inhibitory activity by the colorimetric COX (ovine) inhibitor screening assay and anti-inflammatory activity by the carrageenan-induced rat paw edema assay. 2-(4-Nitrophenyl)-3-(4-tolyl)-4(3H)-quinazolinone showed a maximum COX-2 inhibition of 27.72% at 22 μM concentration in the present series and exhibited a mild anti-inflammatory activity at a dose of 50 mg/kg in carrageenan-induced rat paw edema assay.

Synthesis of Some New 2-Aryl-3-Hetaryl-4(3H) Quinazolones

2-Aryl (alkyl)-benzoxazin-4-ones (I, R = CH3, C6H5, C6H5CH2, p-NO2C6H4) are condensed with 2-amino hetaryls (pyridyl, pyrimidyl, thiazolyl), 1 and 2-amino anthraquinones, p-amino acetophenone and 1,2-diamines like ethylene diamine and o-phenylene diamine.The products are obtained in excellent yields and are characterised by infrared and elemental analysis.