76311-90-5Relevant articles and documents
The Bromination of β-Angelica Lactone Revisited: Synthesis of New 3-Bromo-5-methylene- and 3-Bromo-5-methyl-2(5H)-furanones.
Echagueen, Cristina Ochoa de,Ortuno, Rosa M.
, p. 12457 - 12462 (1994)
Several title compounds have been synthesized efficiently from β-angelica lactone by using simple and mild methods that combine bromination and dehydrobromination or debromination processes accomplished in a convenient order.
Highly effective vinylogous Mukaiyama-Michael reaction catalyzed by silyl methide species generated from 1,1,3,3-tetrakis(trifluoromethanesulfonyl)propane
Takahashi, Arata,Yanai, Hikaru,Zhang, Min,Sonoda, Takaaki,Mishima, Masaaki,Taguchi, Takeo
supporting information; experimental part, p. 1259 - 1265 (2010/04/29)
(Chemical Equation Presented) Silyl methide species in situ generated from 1,1,3,3-tetrakis(trifluoromethanesulfonyl)propane (Tf2CHCH 2CHTf2) performed as an excellent acid catalyst for the vinylogousMukaiyama-Michael reaction of α,β-unsaturated ketones with 2-silyloxyfurans. Notably, the required loading of Tf2CHCH 2CHTf2 to obtain the 1,4-adducts in reasonable yield was significantly low (from 0.05 to 1.0 mol%). This carbon acid-mediatedVMMreaction provides a powerful synthetic methodology to construct highly substituted γ-butenolide structure. 2010 American Chemical Society.
Microwave assisted Suzuki reactions for the preparation of the antifungal 3-aryl-5-methyl-2,5-dihydrofuran-2-ones
Mathews, Christopher J.,Taylor, John,Tyte, Melloney J.,Worthington, Paul A.
, p. 538 - 540 (2007/10/03)
The Suzuki cross-coupling reaction of arylboronic acids with a bromo-furanone has been developed to prepare a series of substituted 2,5-dihydrofuran-2-ones related to the fungal metabolite, incrustoporin. A protocol of microwave heating was introduced to improve synthesis throughput. Georg Thieme Verlag Stuttgart.