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Upstream product

• 214898-04-1 1-(4′-methoxyphenyl)pent-1-yne 
• 26928-26-7 (Z)-1-Fluoro-2-(4-methoxyphenyl)ethylene 
• 2234-82-4 1-propylmagnesium chloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 14374-57-3 1-methoxy-4-(pent-1-en-1-yl)benzene 
• 627-19-0 1-Pentyne 
• 696-62-8 para-iodoanisole 
• 925-90-6 ethylmagnesium bromide 
• 5044-52-0 vinyltriphenylphosphonium bromide 
• 75-03-6 ethyl iodide 
• 106175-54-6 1-(p-methoxyphenyl)propenyl-lithium 
• 74-96-4 ethyl bromide 
• 1779-51-7 n-butyl(triphenyl)phosphonium bromide 

Relevant academic research and scientific papers

Stereoselective Rhodium-Catalyzed Isomerization of Stereoisomeric Mixtures of Arylalkenes

A new efficient method for the synthesis of a high ratio of E -alkenes from E / Z mixtures of alkenes with B 2pin 2in the presence of a rhodium catalyst is described. This reaction features mild reaction conditions, broad functional group tolerance, and highly great application potential.

Electronically Mismatched Cycloaddition Reactions via First-Row Transition Metal, Iron(III)-Polypyridyl Complex

The iron(III)-polypyridyl complex and its derivatives showed sufficient oxidizing potential to act as a one-electron oxidant, producing radical cations from olefins and promoting the efficient radical cation [2 + 2] and [2 + 4] cycloaddition reactions. Subsequent chain propagation afforded trisubstituted cyclobutane or cyclohexene derivatives, and this facile route enables the replacement of rare metals with sustainable, green, and inexpensive iron in radical cation cycloadditions.

Copper- and Nickel-Catalyzed Cross-Coupling Reaction of Monofluoroalkenes with Tertiary, Secondary, and Primary Alkyl and Aryl Grignard Reagents

A highly efficient cross-coupling reaction of monofluoroalkenes with tertiary, secondary, and primary alkyl and aryl Grignard reagents in the presence of a catalytic amount of copper or nickel catalyst, respectively, has been developed. The reactions proceeded smoothly at room temperature, providing (E)-alkene isomers in moderate to high yields. Plausible mechanisms of the Ni-catalyzed coupling reaction of monofluoroalkene with Grignard reagents are suggested.

Facile Light-Mediated Preparation of Small Polymer-Coated Palladium-Nanoparticles and Their Application as Catalysts for Alkyne Semi-Hydrogenation

A facile light-mediated preparation of small palladium nanoparticles (PdNPs) with a diameter of 1.3 nm and low dispersity by using low-priced and readily prepared photoactive polymers is presented. These polymers act as reagents for the photochemical reduction of Pd ions and they are also stabilizers for the PdNPs generated in situ. The PdNP–polymer hybrid materials prepared by this reliable approach are efficient hydrogenation catalysts that show high activity and Z-selectivity in the semi-hydrogenation of alkynes. These PdNP–catalyst hybrid materials can be readily recycled and reused up to five times.

Photooxidizing chromium catalysts for promoting radical cation cycloadditions

The photooxidizing capabilities of selected CrIII complexes for promoting radical cation cycloadditions are described. These complexes have sufficiently long-lived excited states to oxidize electron-rich alkenes, thereby initiating [4+2] processes. These metal species augment the spectrum of catalysts explored in photoredox systems, as they feature unique properties that can result in differential reactivity from the more commonly employed ruthenium or iridium catalysts. Spotlight on chromium: Selected CrIII complexes were investigated for promoting radical cation cycloadditions. These species have sufficiently long-lived excited states to oxidize electron-rich alkenes, thereby initiating [4+2] processes. These metal complexes augment the spectrum of catalysts explored in photoredox systems, featuring properties that can result in differential reactivity from the more common Ru or Ir catalysts.

A study of the reaction of n-BuLi with Ti(Oi-Pr)4 as a method to generate titanacyclopropane and titanacyclopropene species

The use of the combination of reagents Ti(Oi-Pr)4/n-BuLi, introduced by the group of J.J. Eisch in 2001, has only found a few applications so far, with sometimes conflicting observations. This article describes a study aimed at clarifying the nature, the stability and the reactivity of the active organometallic species involved. Reactions with CO2 and other trapping reagents reveal that it is generated within a few minutes at 0 C in THF, where it can be considered to be stable for 30 min. Most of our results are consistent with the expected titanacyclopropane nature of this reagent but some observations suggest that the chemistry at play may be more complicated.

Protonation and Alkykation of 1-Arylpropenyl-lithium

The protonation and alkylation of 1-arylpropenyl-lithium (1a-c) in ether was undertaken systematically; the regio- and stereo-chemistry being influenced by various factors.The characteristic features are as follows. (a) Protonation occurs predominantly at C-3, whereas the sterically more crowded C-1 is the more favoured site for alkylation, and (b) although 1-arylpropenyl-lithium (1) seems to exist mainly as the E-isomer, in some cases the product (3) or (5) having the Z-configuration is produced from attack at C-3 in a significant amount together with the E-isomer, e.g. protonation by oxygen acids in the presence or absence of tetramethylethylenediamine and methylation of the p-methoxy derivative (1a).

REACTIONS EN MILIEU HETEROGENE SOLIDE-LIQUIDE FAIBLEMENT HYDRATE III - LA REACTION DE WITTIG DANS LE SYSTEME CARBONATES ALCALINS/SOLVANT ORGANIQUE PROTIQUE

The use of alkaline carbonates in a slighty hydrated solid-liquid protic organic media allowed the synthesis of alkenes from polyfunctional aldehydes with high yield in a E preferential stereochemistry specially with non-stabilized ylides.It has been shown that the decomposition of the threo betain acts as the determining step of the reaction.