76437-44-0

Basic information

• Product Name: 4-FLUORO-2-NITROBENZYL BROMIDE
• Synonyms: 4-FLUORO-2-NITROBENZYL BROMIDE;2-Nitro-4-fluorobenzyl bromide;1-Bromomethyl-4-fluoro-2-nitrobenzene;2-Bromomethyl-5-fluoronitrobenzene;1-(Bromomethyl)-4-fluoro-2-nitrobenzene, alpha-Bromo-4-fluoro-2-nitrotoluene
• CAS NO: 76437-44-0
• Molecular Formula: C₇H₅BrFNO₂
• Molecular Weight: 234.0225032
• Product Categories: Fluorine series
• Mol File: 76437-44-0.mol

Chemical Properties

• Boiling Point: 273℃
• Flash Point: 113℃
• Appearance: /
• Density: 1.733
• Vapor Pressure: 0.006mmHg at 25°C
• Refractive Index: 1.
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-FLUORO-2-NITROBENZYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-FLUORO-2-NITROBENZYL BROMIDE(76437-44-0)
• EPA Substance Registry System: 4-FLUORO-2-NITROBENZYL BROMIDE(76437-44-0)

Safety Data

• Hazard Codes: C
• Statements: 22-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8 / PGII
• WGK Germany: 3
• Hazardous Substances Data: 76437-44-0(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

InChI:InChI=1/C7H5BrFNO2/c8-4-5-1-2-6(9)3-7(5)10(11)12/h1-3H,4H2

Upstream product

• 20274-69-5 (4-fluoro-3-nitrophenyl)methanol 
• 1043416-40-5 (4-fluoro-2-nitrophenyl)methanol 
• 446-10-6 2-nitro-4-fluorotoluene 
• 100-39-0 benzyl bromide 
• 94-36-0 dibenzoyl peroxide 

Downstream Products

• 402-67-5 3-fluoro-1-nitrobenzene 
• 1006899-36-0 1-(2-amino-4-fluorobenzyl)-3-(4-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethylimidazolidine-2,4-dione 
• 1179329-41-9 diethyl [4-(3-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}ureido)phenyl]phosphonate 
• 1179329-43-1 [4-(3-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}ureido)phenyl]phosphonic acid 
• 1179329-84-0 N-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}sulfamide 
• 1179329-42-0 monoethyl [4-(3-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}ureido)phenyl]phosphonate 
• 1179329-83-9 N-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}N'-tert-butyloxycarbonylsulfamide 
• 1179329-52-2 1-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}-3-(4-methanesulfonylphenyl)sulfamide 
• 1179329-78-2 1-(4-fluoro-2-nitrobenzyl)-3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethylimidazolidine-2,4-dione 
• 1179906-55-8 methyl 2-(3-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}ureido)-2-methylpropionate 
• 708-58-7 2-(4-fluoro-2-nitrophenyl)acetonitrile 

Relevant articles and documents

Intramolecular Pd-catalyzed reductive amination of enolizable sp3-C-H bonds

A palladium-catalyzed reductive cyclization of nitroarenes has been designed to construct sp3-C-NHAr bonds from sp3-C-H bonds by using an enolizable nucleophile to intercept a nitrosoarene intermediate. Exposure of ortho-substituted nitroarenes to 5 mol ?% of Pd(OAc)2 and 10 mol ?% of phenanthroline under 2 atm of CO constructs partially saturated 5-, 6-, or 7-membered N-heterocycles using α-pyridyl carboxylates, malonates, 1,3-dimethylbarbituric acid, 1,3-diones, or difurans as the nucleophile.

Arylchalcogenoarylalkyl-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising these compounds and use thereof

The invention relates to compounds of formula (I) wherein the groups R and R′, A, D, E, G, L, p and R1 to R10 have the stated meanings and to their physiologically compatible salts. Said compounds are suitable, for example, as anti-obesity drugs.

2-oxo-1,3,4-trihydroquinazolinyl derivatives and methods of use

Selected compounds are effective for treatment of diseases, such as cell proliferation or apoptosis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving stroke, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Aminobenzosultam derivatives as lipoxygenase inhibitors

Aminobenzosultam derivatives, which are inhibitors of lipoxygenase, having the formula STR1 and the pharmaceutically acceptable acid addition salts thereof, wherein Ar is cycloalkyl having five to seven carbon atoms, tetrahydropyranyl, pyridyl, oxazolyl,

Halogenated esters

Compounds of formula I wherein R1 and R2 are each selected from halomethyl and halo and R is nitro, cyano, lower alkoxycarbonyl, lower alkylcarbonyl, or di- or trifluoromethyl, and n has a value of zero to four, and compositions comprising them are useful as insecticides in agriculture, horticulture and other outlets. They may optionally be combined with other pesticides and/or synergists. The compounds may be prepared by conventional esterification processes from the corresponding acids and appropriately substituted benzyl alcohols or halides, some of which are novel. STR1