76512-73-7Relevant academic research and scientific papers
Synthesis of Oligodeoxyribonucleotides Using N-Benzyloxycarbonyl-Blocked Nucleosides
Watkins, Bruce E.,Kiely, John S.,Rapoport, Henry
, p. 5702 - 5708 (2007/10/02)
The exo amino groups of 2'-deoxyadenosine and 2'-deoxycytidine have been blocked as the benzyl carbamates, and 2'-deoxyguanosine has been blocked as its 2-N-(benzyloxycarbonyl)carbamate and 6-O-benzyl ether.These blocked nucleosides have been incorporated
ALKYL ARYL BROMOPHOSPHATES: NOUVEAUX REACTIFS DE PHOSPHORYLATION
Thuong, N. T.,Chassignol, M.
, p. 2063 - 2066 (2007/10/02)
La reaction des bromophosphates (5) avec le 5'-O-monomethoxytritylthymidine dans la pyridine conduit facilement soit au nucleoside-3'-phosphotriester (7), soit au nucleoside 3'-phosphodiester (8) selon l'ordre d'addition des reactifs.
