76590-35-7Relevant articles and documents
Iodine/DMSO-Promoted Selective Direct Arylthiation of Anilines with Thiols under Metal-Free Conditions
Zhao, Wenqi,Zhang, Feng,Deng, Guo-Jun
, p. 291 - 301 (2021/01/14)
An iodine-promoted divergent thiolation of unprotected anilines with thiols for the synthesis of sulfide anilines has been described. The combinational use of I2 and DMSO played an important role to realize this kind of transformation without the aid of a
Structure-based design of substituted diphenyl sulfones and sulfoxides as lipophilic inhibitors of thymidylate synthase
Jones, Terence R.,Webber, Stephen E.,Varney, Michael D.,Reddy, M. Rami,Lewis, Kathleen K.,Kathardekar, Vinit,Mazdiyasni, Hormoz,Deal, Judith,Nguyen, Dzuy,Welsh, Katharine M.,Webber, Stephanie,Johnston, Amanda,Matthews, David A.,Smith, Ward W.,Janson, Cheryl A.,Bacquet, Russell J.,Howland, Eleanor F.,Booth, Carol L. J.,Herrmann, Steven M.,Ward, Robert W.,White, Jennifer,Bartlett, Charlotte A.,Morse, Cathy A.
, p. 677 - 683 (2007/10/03)
Six new diphenyl sulfoxide and five new diphenyl sulfones were designed, synthesized, and tested for their inhibition of human and Escherichia coli thymidylate synthase (TS) and of the growth of cells in tissue culture. The best sulfoxide inhibitor of hum
