765912-07-0Relevant articles and documents
Synthesis and hybridization properties of oligonucleotides containing (2S,3R)-9-(2,3,4-trihydroxybutyl)adenine
Ueno, Yoshihito,Ishihara, Shinji,Ito, Yasutomo,Kitade, Yukio
, p. 475 - 487 (2008/02/09)
The synthesis and properties of oligonucleotides (ONs) containing 9-(2,3,4-trihydroxybutyl)adenine, AC2 and AC3, are described. The ON containing AC2 involves the 3′ → 4′ and 3′ → 5′ phosphodiester linkages in the strand,
Synthesis of 2',5'-oligoadenylate analogs containing an adenine acyclonucleoside and their ability to activate human RNase L.
Ueno, Yoshihito,Ishihara, Shinji,Ito, Yasutomo,Kitade, Yukio
, p. 4431 - 4434 (2007/10/03)
This paper described synthesis of 2',5'-oligoadenylate (2-5A) analogs containing the purine acyclonucleoside, 9-[(2'S,3'R)-2',3',4'-trihydroxybutyl]adenine (2). The ability of the analogs to activate recombinant human RNase L was evaluated using 5'-32P-r(