765912-08-1

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 765912-07-0 N⁶-benzoyl-9-[(2'S,3'R)-2',3'-dihydroxy-4'-(4,4'-dimethoxytrityloxy)butyl]adenine 
• 81739-09-5 9-[(2'S,3'R)-4'-hydroxy-2',3'-isopropylidenedioxybutyl]adenine 
• 98-88-4 benzoyl chloride 
• 765912-05-8 N⁶-benzoyl-9-[(2'S,3'R)-2',3',4'-trihydroxybutyl]adenine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 765912-04-7 C₆H₅COC₅H₃N₅CH₂C₂H₂O₂C(CH₃)2CH₂OH 

Relevant academic research and scientific papers

Synthesis of 2',5'-oligoadenylate analogs containing an adenine acyclonucleoside and their ability to activate human RNase L.

This paper described synthesis of 2',5'-oligoadenylate (2-5A) analogs containing the purine acyclonucleoside, 9-[(2'S,3'R)-2',3',4'-trihydroxybutyl]adenine (2). The ability of the analogs to activate recombinant human RNase L was evaluated using 5'-32P-r(

Synthesis and hybridization properties of oligonucleotides containing (2S,3R)-9-(2,3,4-trihydroxybutyl)adenine

The synthesis and properties of oligonucleotides (ONs) containing 9-(2,3,4-trihydroxybutyl)adenine, AC2 and AC3, are described. The ON containing AC2 involves the 3′ → 4′ and 3′ → 5′ phosphodiester linkages in the strand,