76593-98-1Relevant academic research and scientific papers
(±)-7-Oxo-1,2,3,4,4a,5,6,7-octa-hydronaphthalene-1-acetic acid: Catemeric hydrogen bonding and diastereomeric disorder in a bicyclic unsaturated ε-keto acid
Davison, Mark,Thompson, Hugh W.,Lalancette, Roger A.
, p. o242-o244 (2004)
The synthesis and crystal structure of (±)-7-Oxo-1,2,3,4,4a,5,6,7- octa-hydronapthalene-1-acetic acid were discussed. The 68.5:31.5 mixture of diasteroisomers obtained in the synthesis of the compound yielded sharply melting crystals containing the same r
Facile synthesis of oxatricyclic systems with various ring sizes and substituents
Muthusamy, Sengodagounder,Arulananda Babu, Srinivasarao,Gunanathan, Chidambaram,Suresh, Eringathodi,Dastidar, Parthasarathi,Vir Jasra, Raksh
, p. 6307 - 6318 (2007/10/03)
A series of α-diazo carbonyl compounds having cyclopentanone, cyclohexanone and substituted cyclohexanone units with different tether lengths have been synthesized using diazomethane solution or methanesulphonyl azide. The above synthesized α-diazo carbon
ENAMINE CHEMISTRY XX. SYNTHESIS OF FURAN DERIVATIVES BY REDUCTIVE CYCLISATION OF ENAMINES
Carlsson, S.,El-Barbary, A. A.,Lawesson, S.-O.
, p. 643 - 650 (2007/10/02)
Enamines, I, prepared from cyclohexanones or cyclopentanones and pyrrolidine are alkylated with 2-bromoesters (ethyl 2-bromoethanoate, ethyl 2-bromopropanoate, methyl 2-bromopropanoate) to give new enamines, II, which after treatment with LiAlH4 undergo reductive cyclisation reactions giving the furan derivatives, III (7a-pyrrolidino-octahydrobenzofurans, 6a-pyrrolidino-hexahydrocyclopentafurans) in almost quantitative yields.The compounds III are hydrolyzed with hydrochloric acid to octahydrobenzofuran-7a-ols or hexahydrocyclopentafuran-6a-ols, IV.Elimination of pyrrolidine from III with oxalic acid in anhydrous dioxane yields condensed dihydrofurans, V.
